Division of Experimental Pathology

FacultyServices Projects PublicationsResearch Staff


The division has a fully equipped histopathology facility, tissue culture facility, cryopreservation of biological samples, immunohistochemistry etc


The services offered by the lab include autopsy of small animals, grossing, sampling, tissue processing, embedding, microtomy and different staining methods like hematoxylin & eosin and special stains. The lab also offers histopathology evaluation.


1. Development of Bioartifical skin grafts from mammalian derived scaffolds. Funding agency: Department of Biotechnology, Government of India.

2. Prototyping of skin-graft substitutes for wound healing applications using cholecyst-derived extracellular matrix. Funding agency: SCTIMST.

3. Development of Technologies for isolation and characterization of tissue-engineering-scaffolds from mammalian organs and tissues. Funding agency: Department of Biotechnology, Government of India

  1. Nampi, PP C.C. Kartha, G. Jose, A.K.P. Rajan, T. Anilkumar, H. Varma, Sol-Gel Nanoporous Silica As Substrate For Immobilization Of Conjugated Biomolecules For Application As Fluorescence Resonance Energy Transfer (FRET) Based Biosensor, Sensors and Actuators B: Chemical (2013) 185: 252-257
  2. Deepa Revi, Willi Paul, Anilkumar TV, Sharma CP. Differential healing of full thickness rabbit skin wound by fibroblast loaded chitosan sponge. Journal of Biomaterials and Tissue Engineering (2013) 3, 261-272.
  3. Kumar PT Sudheesh, VK Lakshmanan, TV Anilkumar, C Ramya, P Reshmi, AG Unnikrishnan, SV Nair, J Rangasamy (2012) Flexible and micro-porous chitosan hydrogel/nano ZnO composite bandages for wound dressing: in vitro and in vivo evaluation. ACS Applied Material and Interfaces, 2012, 4 (5): 2618-2629
  4. Jaseer Muhamed, Deepa Revi, Roy Joseph, T Anilkumar Phenotypic modulation of cell types around implanted polyethylene terephthalate fabric in rabbit muscle. Toxicologic Pathology. Toxicologic Pathology 2013;41(3):497-507
  5. Anilkumar TV, JaseerMuhammed, Anumol Jose, Arun Jyothi, Mohanan PV and Lissy K Krishnan (2011). Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound. Biologicals, 39: 81-88.
  6. Anilkumar TV, Harikrishnan VS, Thulaseedharan, Sreeja KR, Deepa, R Fernandez AC (2011) Immunohistochemistry and confocal microscopy of rat mammary gland scirrhous carcinoma Indian Journal of Veterinary Pathology, 35 (1): 108-110.
  7. Anilkumar TV, Vineetha VP, Thulaseedharan and Harikrishnan VS (2009) Endomyocardial fibrosis in a laboratory rat, Journal of Indian Veterinary Association, 7 (2): 90-92
  8. Swathy SS; Anilkumar TV (2008). Healing response of skeletal muscle to implanted biomaterials in rabbit: an immunohistochemical study of desmin and alpha-smooth-muscle-actin positive cells Indian Journal of Veterinary Pathology, 31 (2): 113-119.
  9. Anilkumar TV, Shelma R, Joseph R, Mohanan, PV, Muraleedharan CV (2007) Impalnt Pathology of polyvinylidene fluoride coated polyethylene tetrathalate fabric in rabbits. Indian Journal of Veterinary Pathology, 31 (1): 11-16.
  10. Nishi KK; Antony M; Mohanan PV; Anilkumar TV; Loiseau PM; Jayakrishnan A (2007). Amphotericin B-gum Arabic conjugates: synthesis, toxicity, bioavailability and activities against Leishmania and fungi. Pharmaceutical Research, 24(5): 971-80.
  1. Anilkumar TV (Provisional patent No. 877-CHE-2012): A simplified procedure for isolating tissue-engineering-scaffolds from small intestinal submucosa of warm blooded animals
  2. Anilkumar TV (Provisional patent No. 985-CHE-2012): A simplified procedure for isolating tissue-engineering-scaffold from cholecyst
  3. Anilkumar TV (Provisional patent No. 1176-CHE-2012): A process for delaminating tissue layers of urinary bladder for isolating extracellular matrix components
  4. Anilkumar.TV, Deepa Revi and Jaseer Muhamed CJ (Provisional Patent No2338/CHE/2013): A procedure for fabricating xenograft using mammalian cholecyst-derived extracellular matrix for wound healing applications

1. Tissue Engineering Scaffolds of Animal (mammalian) Origin: The research theme centers on the development and use of decellularised animal tissues as biomaterials for tissue engineering application. The lab has developed bio artificial skin grafts using porcine sub mucosal extracellular matrix extracted from small intestine, urinary bladder and gall bladder. The lab also interest on study of immune response pathways activated by these scaffold xenografts in animal models.

2. Pathology of Laboratory Animals