People - Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (SCTIMST)

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श्री चित्रा तिरुनाल आयुर्विज्ञान और प्रौद्योगिकी संस्थान, त्रिवेंद्रम

विज्ञान एवं प्रौद्योगिकी विभाग, भारत सरकार के अधीन एक राष्ट्रीय महत्व का संस्थान

Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum

An Institution of National Importance, Department of Science and Technology, Govt. of India

HOSPITAL

BMT

AMCHSS

ACADEMIC

JOURNAL

Dr. Sachin J. Shenoy

Scientist 'G'

Phone : +91 471 2520223/243(O), +91 9447432656 (Mob)

Email :

Academic Qualification Professional Record Publications

Academic Qualifications

Master of Veterinary Science; College of Veterinary & Animal Sciences, Kerala Agricultural University, Mannuthy, Thrissur-680 651; 2004 .

Bachelor of Veterinary Science & Animal Husbanbry; College of Veterinary & Animal Sciences, Kerala Agricultural University, Mannuthy, Thrissur-680 651; 2001.

Professional Record

Scientist - C, D, E,F ; Division of In-vivo Models & Testing, Biomedical Technology Wing, SCTIMST; 09/08/2006 - Till date.

Veterinary Surgeon; Division of In-vivo Models & Testing, Biomedical Technology Wing, SCTIMST; 28/09/2005 - 04/08/2006.

Veterinary Surgeon; Division of Vivarium, Biomedical Technology Wing, SCTIMST; 16/03/2005 - 25/09/2005.

Teaching Assistant; University Livestock Farm, Kerala Agricultural University, Mannuthy Thrissur;15/12/2004 - 10/03/2005.

Veterinary Surgeon; Division of Vivarium, Biomedical Technology Wing, SCTIMST; 13/12/2002 - 03/10/2003.

DST-IIPA Silver Medal for having secured the second position among the participants in the 9th Foundation Training Programme for Scientists and Technologists sponsored by Department of Science and Technology at Indian Institute of Public Administration, New Delhi in 2010.

Area of Interest

Experimental Animal Surgery, Anaesthesia and Perioperative Acute Care.

Current Activities

Assistance in conduct of animal studies for proof of concept and preclinical testing of medical devices like coronary stents, heart valves, left ventricular assist devices, vascular grafts and dental composites in large animal models.

Routine management of Large Animal Facility, DIMT.

Membership

Member, Indian Veterinary Association

Life Member, Society for Biomaterials and Artificial Organs - India.

Life member, Laboratory Animal Science Association of India.

Life member, Indian Society for Veterinary Surgery.

On-going Projects

Principal Investigator: Over Head Fund (OHF) project "Characterization and Documentation of base line reference data of inhouse bred Ankamali Swine for application in Biomedical Research".

Team

Ms Smitha P, Technical Assistant (Anaesthesia).

Mr Prem Mohan, Technical Assistant (Lab) .

Mr Manoj Kumar K, Animal Caretaker.

Mr Biju V, Animal Handler.

No. of Publications

Publications

Article

Vijayan VM, Shenoy SJ, Victor SP, Muthu J., Stimulus responsive nanogel with innate near IR fluorescent capability for drug delivery and bioimaging. , Colloids and Surfaces B: Biointerfaces. , 2016, Oct 1;146:84-96., https://doi.org/10.1016/j.colsurfb.2016.05.059

Nair RS, Sobhan PK, Shenoy SJ, Prabhu MA, Rema AM, Ramachandran S, C Geetha S, V Pratheesh K, Mony MP, Raj R, Anilkumar TV., A porcine cholecystic extracellular matrix conductive scaffold for cardiac tissue repair., Journal of Biomedical Materials Research Part B: Applied Biomaterials., 2022, Mar 19., https://doi.org/10.1002/jbm.b.35058

Dayamon D. M., Sachin J. S., Vineeth M. R., Umashankar P. R., Electroencephalographic Evaluation of Thiopentone and Propofol Anaesthesia in Dogs. JIVA., JOURNAL OF INDIAN VETERINARY ASSOCIATION, KERALA, 2021, Dec 19 (3) : 27-36., DOI: 10.55296/JIVA/19.3.2021.27-36.

Saraswathy A, Nazeer SS, Nimi N, Santhakumar H, Suma PR, Jibin K, Victor M, Fernandez FB, Arumugam S, Shenoy SJ, Varma PR., Asialoglycoprotein receptor targeted optical and magnetic resonance imaging and therapy of liver fibrosis using pullulan stabilized multi-functional iron oxide nanoprobe., Scientific Reports., 2021, Sep 15;11(1):1-1., https://www.nature.com/articles/s41598-021-97808-0

Mony MP, Shenoy SJ, Raj R, Geetha CS, Pratheesh KV, Nair RS, Purnima C, Anilkumar TV., Gelatin-Modified Cholecyst-Derived Scaffold Promotes Angiogenesis and Faster Healing of Diabetic Wounds., ACS Applied Bio Materials., 2021, Mar 10;4(4):3320-31., https://doi.org/10.1021/acsabm.0c01648

Raj R, Shenoy SJ, Mony MP, Pratheesh KV, Nair RS, Geetha CS, Sobhan PK, Purnima C, Anilkumar TV., Surface Modification of Polypropylene Mesh with a Porcine Cholecystic Extracellular Matrix Hydrogel for Mitigating Host Tissue Reaction., ACS Applied Bio Materials., 2021, Mar 10;4(4):3304-19., https://doi.org/10.1021/acsabm.0c01627

Harikrishnan VS, Shenoy SJ, Ranaraj VR, Sukhija S, Oloyo AK., A report on less-severe, long-duration persistent hind-limb ischemia surgical rabbit model., Journal of the Hellenic Veterinary Medical Society., 2021, 72(4):3455-62., https://doi.org/10.12681/jhvms.29395

Sathee D, Shenoy SJ, Anil A. Sabareeswaran A, Lissy Kalliyana Krishnan., Combinatorial Application of Hyaluronic Acid and Curcumin-Albumin Conjugate for Cartilage Repair in TNF Induced Inflammation in Rabbit Knee Joint., Archives of Clinical and Biomedical Research., 2021, 5:519-37., https://www.fortunejournals.com/articles/combinatorial-application-of-hyaluronic-acid-and-curcuminalbumin-conjugate-for-cartilage-repair-in-tnf-alpha-induced-inflammation-.html

Venugopal B, Shenoy SJ, Mohan S, Anil Kumar PR, Kumary TV., Bioengineered corneal epithelial cell sheet from mesenchymal stem cells- A functional alternative to limbal stem cells for ocular surface reconstruction., Journal of Biomedical Materials Research Part B: Applied Biomaterials., 2020, Apr;108(3):1033-45., https://doi.org/10.1002/jbm.b.34455

Nair RV, Nair LV, Govindachar DM, Santhakumar H, Nazeer SS, Rekha CR, Shenoy SJ, Periyasamy G, Jayasree RS., Luminescent Gold Nanorods To Enhance the Near???Infrared Emission of a Photosensitizer for Targeted Cancer Imaging and Dual Therapy:, Experimental and Theoretical Approach. Chemistry???A European Journal., 2020, Mar 2;26(13):2826-36., https://doi.org/10.1002/chem.201904952

more...

Anitha R, Vaikkath D, Shenoy SJ, Nair PD., Tissue engineered islet like cell clusters generated from adipose tissue derived stem cells on three dimensional electrospun scaffolds can reverse diabetes in an experimental rat model and the role of porosity of scaffolds on cluster differentiation., Journal of Biomedical Materials Research Part A., 2020, Mar;108(3):749-59., https://doi.org/10.1002/jbm.a.36854

Subha S, Shenoy SJ, Anil A, Sabareeswaran A, Deepthi AN, Krishnan LK., Fibrin hydrogel aided cardiac progenitor cell delivery enhances regenerative tendency in myocardial infarct model., Archives of Clinical and Biomedical Research., 2020, 4(5):513-41., https://www.fortuneonline.org/articles/fibrin-hydrogel-aided-cardiac-progenitor-cell-delivery-enhances-regenerative-tendency-in-myocardial-infarct-model.html

Jibin K, Prasad JS, Saranya G, Shenoy SJ, Maiti KK, Jayasree RS., Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy., Biomaterials Science., 2020, 8(12):3381-91., https://doi.org/10.1039/D0BM00312C

Suma PR, Padmanabhan RA, Telukutla SR, Ravindran R, Velikkakath AK, Dekiwadia CD, Paul W, Shenoy SJ, Laloraya M, Srinivasula SM, Bhosale SV., Paradigm of Vanadium pentoxide nanoparticle-induced autophagy and apoptosis in triple-negative breast cancer cells., BioRxiv., 2019, Jan 1:810200., doi: https://doi.org/10.1101/810200

Vijayan VM, Beeran AE, Shenoy SJ, Muthu J, Thomas V., New magneto-fluorescent hybrid polymer nanogel for theranostic applications., ACS Applied Bio Materials., 2019, Jan 9;2(2):757-68., https://doi.org/10.1021/acsabm.8b00616

Nazeer SS, Saraswathy A, Shenoy SJ, Jayasree RS., Fluorescence spectroscopy as an efficient tool for staging the degree of liver fibrosis: an in vivo comparison with MRI., Scientific reports., 2018, Jul 20;8(1):1-1., https://www.nature.com/articles/s41598-018-29370-1

Nimi N, Saraswathy A, Nazeer SS, Francis N, Shenoy SJ, Jayasree RS., Multifunctional hybrid nanoconstruct of zerovalent iron and carbon dots for magnetic resonance angiography and optical imaging: an in vivo study., Biomaterials., 2018, Jul 1;171:46-56., https://doi.org/10.1016/j.biomaterials.2018.04.012

Santhakumar H, Nair R, Philips DS, Shenoy SJ, Thekkuveettil A, Ajayaghosh A, Jayasree R, Real time imaging and dynamics of hippocampal Zn2+ under epileptic condition using a ratiometric fluorescent probe., Scientific reports., 2018, Jun 13;8(1):1-1., https://www.nature.com/articles/s41598-018-27029-5

Chandran S, Shenoy SJ, Nair RP, Varma HK, John A., Strontium Hydroxyapatite scaffolds engineered with stem cells aid osteointegration and osteogenesis in osteoporotic sheep model., Colloids and Surfaces B: Biointerfaces., 2018, Mar 1;163:346-54., https://doi.org/10.1016/j.colsurfb.2017.12.048

Unnikrishnan M, Umashankar PR, Viswanathan S, Savlania A, Joseph R, Muraleedharan CV, Agrawal V, Shenoy SJ, Krishnan LK, Mohanan PV, Sabareeswaran A., Preclinical evaluation of hydrogel sealed fluropassivated indigenous vascular prosthesis., The Indian Journal of Medical Research., 2017, Nov;146(5):646, https://doi.org/10.4103%2Fijmr.IJMR_1933_15

Umashankar PR, Sabareeswaran A, Shenoy SJ., Long term healing of mildly cross linked decellularized bovine pericardial aortic patch., Journal of Biomedical Materials Research Part B: Applied Biomaterials., 2017, Oct 1;105(7):2145-52., https://doi.org/10.1002/jbm.b.33755

Vijayan VM, Shenoy SJ, Muthu J., Octreotide-conjugated fluorescent PEGylated polymeric nanogel for theranostic applications., Materials Science and Engineering: C., 2017, Jul 1;76:490-500., https://doi.org/10.1016/j.msec.2017.03.125

Nair LV, Nair RV, Shenoy SJ, Thekkuveettil A, Jayasree RS., Blood brain barrier permeable gold nanocluster for targeted brain imaging and therapy: an in vitro and in vivo study., Journal of Materials Chemistry B., 2017, 5(42):8314-21., https://doi.org/10.1039/C7TB02247F

Payanam RU, Shenoy SJ, Arumugham S., Improved Pig Model to Evaluate Heart Valve Thrombosis., The Journal of heart valve disease., 2016, Sep;25(5):606., https://pubmed.ncbi.nlm.nih.gov/28238243/

Despang F, Bernhardt A, Lode A, Dittrich R, Hanke T, Shenoy SJ, Mani S, John A, Gelinsky M., Synthesis and physicochemical, in vitro and in vivo evaluation of an anisotropic, nanocrystalline hydroxyapatite bisque scaffold with parallel???aligned pores mimicking the microstructure of cortical bone., Journal of Tissue Engineering and Regenerative Medicine., 2015, Dec;9(12):E152-66., https://doi.org/10.1002/term.1729

Basu, B; Sabareeswaran, A; Sachin, J Shenoy., Biocompatibility property of 100% strontium-substituted SiO2?Al2O3?P2O5?CaO?CaF2 glass ceramics over 26 weeks implantation in rabbit model: Histology and micro Computed Tomography analysis ., Journal of Biomedical Materials Research Part B: Applied Biomaterials,, 2015, 01-Oct-14, DOI: 10.1002/jbm.b.33270.

Saraswathy, A; Nazeer, S S; Nimi, N; Sabareeswaran, A; Sachin, J Shenoy; Jayashree, R S., Synthesis and characterization of dextran stabilized superparamagnetic iron oxide nanoparticles for in vivo MR imaging of liver fibrosis., Carbohydrate Polymers., 2014, 30;101:760-8., DOI:10.1016/j.carbpol.2013.10.015.

Sabareeswaran, A; Basu, B; Sachin, J Shenoy; Jaffer Z, Saha, N; Stamboulis, A ., Early osseointegration of strontium containing glass ceramic in a rabbit model., Biomaterials., 2013, 34(37):9278-86., DOI:10.1016/j.biomaterials.2013.08.070

Despang F, Bernhardlt A, Lode A, Dittrich R, Hanke T, Sachin, J Shenoy, Mani S, John A and Gelinsky M., Synthesis and physicochemical, in vitro and in vivo evaluation of an anisotropic, nanocrystalline hydroxyapatite bisque scaffold with parallel-aligned pores mimicking the microstructure of cortical bone., Journal of Tissue Engineering And Regenerative Medicine., 2013, , DOI: 10.1002/term.1729.

Vidhya L, Sachin, J Shenoy, Umashankar, PR., Feed Induced Chronic Copper Toxicosis In Stall-Fed Sheep., International Journal of Livestock Research, 2012, 2(3): 219-222., www.scopemed.org/?mno=19074

Indu, NN; Lekshmi, V;Sachin, J Shenoy; Umashankar, PR., Hypokaleamia with Respiratory Alkalosis in Anaesthetized Goats., Indian Veterinary Journal., 2012, 89(9): 51-52

Fernandez, FB; Sachin, Shenoy; Babu, SS; Varma, HK; John, A., Short-term studies using ceramic scaffolds in lapine model for osteochondral defect amelioration., Biomedical Materials., 2012, 7(3):035005., PMID:22406527.

Sujesh, S; Rajeev, A; Sachin, J Shenoy; Umashankar, PR;and Muraleedharan, C.V;, An automated data acquisition system for capturing physiological parameters during animal trials of artificial heart valves., Int. J. Biomedical Engineering and Technology,, 2012, 10(1): 70-83., DOI:10.1504/IJBET.2012.049326

Kurian, M V;Umasankar, P R; Sabareeswaran, A; Sachin, J Shenoy; Subban, V; Joseph, M K., A new concept in the sewing rings for mechanical heart valves., Asian Cardiovasc Thorac Ann., 2012, 20 (4): 409-417., DOI: 10.1177/0218492312438741

Beena, G Mohan; Sachin, J Shenoy;Suresh, Babu S; Varma, HK; John, A. ., Strontium calcium phosphate for the repair of leporine (Oryctolagus cuniculus) ulna segmental defect., Journal of Biomedical Mater Res Part A, 2012, 101A : 261-271, DOI: 10.1002/jbm.a.34324

Kaur, S; Harikrishnan, VS; Sachin, J Shenoy; Radhakrishnan, NS;Uruno, A;Sugawara, A; Kartha, CC., Transfection of Endothelial Nitric Oxide Synthase Gene Improves Angiogenic Efficacy of Endothelial Progenitor Cells in Rabbits with Hindlimb Ischemia., Journal of Clinical & Experimental Cardiology, 2011, 2-140, DOI:10.4172/2155-9880.1000140

Ganesh,.G;Sachin, J. Shenoy;.Umashankar, P.R, Long Duration Anaesthetic Regimen for Major Surgical Procedures in Goats., Indian Veterinary Journal, 2011, 88(5) : 20-21.

Nair, MB; Varma, HK; Menon, KV; Sachin, J Shenoy; John, A., Reconstruction of goat femur segmental defects using triphasic ceramic-coated hydroxyapatite in combination with autologous cells and platelet-rich plasma., Acta Biomaterialia, 2009, 5:1742-1755., DOI:10.1016/j.actbio.2009.01.009

Nair, MB; Varma, HK; Menon, KV;Sachin, J Shenoy; John, A., Tissue regeneration and repair of goat segmental femur defect with bioactive triphasic ceramic-coated hydroxyapatite., Journal of Biomedical Materials Research Part A., 2009, 91(3):855-65., DOI:10.1002/jbm.a.32239

Harikrishnan, VS; Sachin, J Shenoy;Umashankar, PR, Anesthetic Regimen for Coronary Stenting in Porcine Model., The Indian Veterinary Journal, 2006, 83(5):486-489

Sachin, J Shenoy;Umashankar PR;Lal GAV, Management of Damaged Lumbosacral Plexus Due to Foetopelvic Disproportion in a Gilt., Indian Veterinary Journal, 2006, 83(11): 1204-1205

Ravishankar, C; Muthuramalingam, M; Sachin, J Shenoy; Mini M; Jayaprakasan, V., Isolation of Streptococcus suis from a fatal case of Pneumonitis in a Boar., The Indian Veterinary Journal, 2005, 82(8): 910-911, http://agris.fao.org/agris-search/search.do?recordID=IN2006001627