Dr. Divya M. S.
Scientist 'C'
Phone :

Ph.D. Biotechnology, Rajiv Gandhi Centre for Biotechnology, University of Kerala, Kerala, 2014

M.Sc. Microbiology, Department of Biotechnology & Microbiology, School of Life Sciences, Kannur University, Kerala, 2006

B.Sc. Biotechnology, University of Calicut, Kerala, 2004

Scientist C: 2018- till date, Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India

RIKEN-Special Postdoctoral Researcher (SPDR): 2018, Laboratory for Advanced Genomics Circuit, RIKEN Center for Integrative Medicine Science (IMS), Yokohama, Japan

Post-doctoral Researcher: 2015-2018, Cell Conversion Technology Team, RIKEN-Center for Life Science Technologies (CLST), Yokohama, Japan (*RIKEN-CLST merged with RIKEN-Center for Integrative Medicine Science from April 2018)

Post-doctoral Researcher (PBC Postdoctoral Fellowship): 2014-2015, Meshorer Lab, Department of Genetics, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Israel

Senior Researcher Fellow: 2013-2014, Neural Stem Cell biology laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India

Fulbright Visiting Research Scholar: 2012-2013, Department of Biology, Johns Hopkins University, Baltimore, MD, USA

Graduate Research Scholar: 2007-2013, Neural Stem Cell biology laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India

University first rank and Gold medalist, M.Sc. Microbiology (2006), Department of Biotechnology & Microbiology, School of Life Sciences, Kannur University, Kerala, India.

Dr. M. R. Das Career Award (2014) for noted professional achievements during the graduate research tenure at Rajiv Gandhi Centre for Biotechnology, Kerala, India.

Rajiv Gandhi Centre for Biotechnology Merit award (2011) for the best graduate research work presentation, Kerala, India

Fate-specific differentiation of pluripotent stem cells, Regenerative medicine, Modelling neurological and neurodevelopmental disorders using patient-specific induced pluripotent stem cells (iPSCs) and cerebral organoids, Role of long non-coding RNA in pluripotency and lineage specific differentiation

RIKEN-Special Postdoctoral Researcher (SPDR) fellowship (2018), Programs for Junior Scientists, RIKEN, Japan

PBC Fellowship for outstanding Post-Doctoral Researchers (2014), The Planning and Budgeting Committee, Council for Higher Education, Israel

Fulbright-Nehru Doctoral Research Fellowship (2012) for carrying out graduate research in US universities

Indian Council of Medical Research-Junior Research Fellowship (2007), Government of India for pursuing graduate research in National Institutes of India

The Human Genome Organization (HUGO)

Dynamic modelling of ??-synucleinopathy pathology using hiPSC-derived cerebral organoids for biomarkers and drug screening application, Funding: Seed grant from "Accelerator program for Discovery in Brain disorders using Stem cells (ADBS)" program, a collaborative initiative by National Centre for Biological Sciences (NCBS), the Institute for Stem Cell Biology and Regenerative Medicine (inStem) and the National Institute for Mental Health and Neurosciences (NIMHANS) (https://www.ncbs.res.in/adbs/seed-grants).

Krishnapriya Chandrababu- Project Fellow


Luginbuhl, J., Divya, M. S., Shin, J. W., The Essentiality of Non-Coding RNAs in Cell Reprogramming, Non-coding RNA Research, 2017, 2, 74-82, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096403/
Divya, M. S., Abdul, R.V., Schmidt, T., Soundararajan, L., Hattar, S. and James, J., Intraocular injection of ES cell-derived neural progenitors improves visual function in retinal ganglion cell-depleted mouse models, Frontiers in Cellular Neuroscience, 2017, 1, 11:295, https://www.ncbi.nlm.nih.gov/pubmed/28979193/
Schlesinger, S., Kaffe, B., Melcer, S., Aguilera, J. D., Divya, M. S., Kaplan, T. and Meshorer, E., A hyperdynamic H3.3 nucleosome marks promoter regions in pluripotent embryonic stem cells, Nucleic Acids Research, 2017, 45:12181-12194, https://www.ncbi.nlm.nih.gov/pubmed/29036702
Divya, T.S., Lalitha, S., Parvathy, S., Subashini, C., Sanalkumar, R., Dhanesh, S.B., Rasheed, V.A., Divya, M.S., Tole, S., and James, J., Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrn?3 in Cerebellar Granule Neuron progenitors during development, Scientific Reports, 2016, 21.317361111111111, https://www.ncbi.nlm.nih.gov/pubmed/27452274/
Rasheed, V. A., Sreekanth, S., Dhanesh, S. B., Divya, M. S., Divya, T. S., Akhila, P. K., Subashini, C., Chandrika Sivakumar, K., Das, A. V. and James, J., Developmental wave of Brn3b expression leading to RGC fate specification is synergistically maintained by miR-23a and miR-374, Developmental Neurobiology, 2014, 74 (12):1155-1171, https://www.ncbi.nlm.nih.gov/pubmed/24838392
Srivastava, N., Venugopalan, V., Divya, M. S., Rasheed, V A., James, J. & Narayan, K., Neuronal differentiation of embryonic stem cell derived neuronal progenitors can be regulated by stretchable conducting polymers, Tissue Engineering. Part A, 2013, 19 (17-18): 1984-1993, https://www.ncbi.nlm.nih.gov/pubmed/23544950
Indulekha, C. L., Divya, T. S., Divya, M. S., Sanalkumar, R., Rasheed, V. A., Dhanesh, S. B., Sebin, A., George, A. & James, J., Hes-1 regulates the excitatory fate of neural progenitors through modulation of Tlx3 (HOX11L2) expression, Cellular and Molecular Life Sciences, 2012, 69, 611-627, https://www.ncbi.nlm.nih.gov/pubmed/21744064
Sobhan, P. K., Seervi, M., Joseph, J., Varghese, S., Pillai, P. R., Divya, M. S., James, J., George, R. E., Elizabeth, K. & Santhoshkumar, T., Immortalized functional endothelial progenitor cell lines from Umbilical Cord Blood for vascular tissue engineering, Tissue Engineering Part C: Methods, 2012, 18, 890-902, https://www.ncbi.nlm.nih.gov/pubmed/22889128
Divya, M. S., Roshin, G. E., Divya, T. S., Rasheed, V. A., Santhoshkumar, T. R., Elizabeth, K. E., James, J. & Pillai, R. M., Umbilical cord blood-derived mesenchymal stem cells consist of a unique population of progenitors co-expressing mesenchymal stem cell and neuronal markers capable of instantaneous neuronal differentiation, Stem Cell Research & Therapy, 2012, 3, 1-16, https://www.ncbi.nlm.nih.gov/pubmed/23253356
Sanalkumar, R., Indulekha, C. L., Divya, T. S., Divya, M. S., Anto, R. J., Vinod, B., Vidyanand, S., Jagatha, B., Venugopal, S. & James, J., ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes?1 expression and synergistically activates the expression of Hes?1 in Notch?dependent neural progenitors, Journal of Neurochemistry, 2010, 113, 807-818, https://www.ncbi.nlm.nih.gov/pubmed/20067572