Dr. Madhusoodanan U. K.
Additional Professor
Phone : 0471-2524478 (O), 8157897692

PhD-Department of Biochemistry, Indian Institute of Science, Bangalore, 2009

MSc-Medical Biochemistry, KMC Manipal, Manipal University (MAHE), 2002

BSc-Microbiology, Kannur University, 1999

Additional Professor, Department of Biochemistry, SCTIMST, January 2024-

Associate Professor, Department of Biochemistry, SCTIMST, January 2021-December 2023

Assistant Professor - Department of Biochemistry, SCTIMST, October 2017-December 2020

Research Scientist - Molecular Oncology, MVRCCRI, Calicut, 2017

Post Doctoral fellow - IFOM-The FIRC Institute of Molecular Oncology, MIlan, Italy- 2009-2016

JRF-NET CSIR and ICMR (2003)

Invited speaker in international conferences

Genetic and Molecular basis of rare inherited disorders

Circulating exosomal-miRNAs as disease indicators for neurodegenerative diseases

Development of biochemical assays for rare neurodegenerative diseases diagnosis

Post doctoral fellowship funded by European Research Council (ERC-2009-StG ERC-SG) - Regulatory mechanisms coordinating replication integrity and intra-S repair

Welcome trust Visiting fellow (February to April 2010), NCBR, Masaryk University, Brno, Czech Republic

Executive Committee Member, Indian Society for Extracellular Vesicles (InSEV)

Life member, Society of Biological Chemists (SBC-India)

Life member, Academy of Cardiovascular Sciences

Principal Investigator: Absolute measurement of Glucocerobrosidase activity for monitoring lysosomal dysfunction in Parkinsons disease-ICMR (2023-2025)

Co-PI: Contemporary outcomes in cardiac channelopathies guided by Genotype-based management-ICMR (2021-2025)

Co-I: Prognostic value of circulating microRNAs in Heart Failure-ICMR (2021-2023)

Co-I: ICMR-Center for Advanced Research and Excellence (CARE) in heart failure-ICMR (2019-2024)

Co-I: Genetic Architecture of Parkinsons disease-The Michael J. Fox Foundation (2019-2022)

Co-PI: A whole exome sequencing study ? in Moyamoya disease in the Indian population-ICMR (2023-2025)

Principal Investigator: Identification and characterization of exosomal proteins in Parkinson?s Disease Patients-ICMR (2021-2024)

Principal Investigator: Detection of Circulating Exosomal-Ubiquitinated Proteins in Parkinsons Disease-Seed Fund-SCTIMST (2019-2021)

Co-PI: Establishment of A Biorepository of Epilepsy and Investigating the Relation of Multidrug Transporter Polymorphism with Fetal Malformations Based on The Repository -DBT (2017-2020)

Co-Invest: Development of real time RT-PCR assay for detection of SARS-CoV2-TDF fund-SCTIMST (2020-2021)

Four days Training in Laboratory Quality Management System (IA & QMS as per ISO15189) accredited by National Accreditation Board for Education and Training (NABET), Quality council of India

Organizing committee member: Biochemistry Talks- Department of Biochemistry, SCTIMST

Scientific Affairs Committee member: 39th Annual Conference of Indian Association for Cancer Research (IACR-2020) at Trivandrum on 5th -7th February 2020

Faculty and moderator for a session in The Heart Failure Conflux, organised by the Heart Failure Assiciation of India

PhD Students: Aishwarya Babu, Priya Nataraj

JRF: Achanya S Jayan

Annual Investigators Meeting-Global Parkinson?s Genetics Program (GP2), Copenhagen, Denmark on 24-26th August, 2023

5th Chromosome Stability Meeting, Dec 14-18, 2022, IISER, Trivandrum

39th Annual Conference of Indian Association for Cancer Research (IACR-2020) at Trivandrum on 5th -7th February 2020.

10th DAE-BRNS Life Science Symposium-2019 (LSS-2019), BARC, Mumbai, March 28-30, 2019

Chromosome Stability 2018 meeting, December 14-17, 2018, JNCASR, Bangalore

10th Young Investigator Meeting (YIM 2018), Mar 5-9, 2018, Trivandrum

Indo-French Conference (Indo-French Centre for Promotion of Advanced Research, IFCPAR/CEFIPRA), December 4-5, 2017, Bangalore.

CME on the occasion of World Microbiome Day, organized by Department of Medical Microbiology & Department of Medical Biochemistry, AKG Co-operative Institute of Health Sciences, Kannur on June 27, 2022

Emerging Trends and Fronters in Applied Microbiology and Biotechnology, organised by St. Pius X College, Rajapuram, Kasaragod on March 10th 2022 (Online)

Emerging trends in Neurotherapeutics, organized by at the department of Biochemistry, St. Thomas College, Palai on December 15th, 2021 (online)

Special lecture on Basic Concepts of Diet and Nutrition, Department of Yoga Studies, Central University of Kerala, October 2020, online.

National Workshop Biovista-2020, Department of Biochemistry, Malankara Catholic College, Kaliakkavilai, Tamil Nadu, on February 4th, 2020.

National Symposium on Advances in Biosciences(SEIB 2019), Inter University Centre for Evolutionary and Integrative Biology (iCEIB) of the University of Kerala, April 27, 2019

National seminar on Omics approaches in Biotechnology at the department of biotechnology, Govt college, Kariavattom on February 15th, 2019

National seminar on New horizons in cancer treatment and prevention: from bench to bedside, Mar 16-17, SN college, Kollam, 2018

Cardio-vascular pathology update, Mar 11-12, SCTIMST, 2018

Reviewer: Journal of Cell Communication and Signaling, Asian Pacific Journal of Tropical Medicine, Cell and Tissue Banking, Journal of Chemistry, Human Gene, Cureus


Asha Kishore, Marc Sturm, Kanchana Soman Pillai, Christopher Hakkaart, Divya Kalikavil Puthanveedu, Madhusoodanan Urulangodi, Syam Krishnan, Ashwin Ashok Kumar-Sreelatha, Roopa Rajan, Pramod Kumar Pal, Ravi Yadav, Gangadhara Sarma, Nicolas Casadei, Thomas Gasser, Peter Bauer, Olaf Riess, Manu Sharma , Resequencing the complete SNCA locus in Indian patients with Parkinson?s disease. , npj Parkinson?s Disease, 2024, 10(1):85 , https://doi.org/10.1038/s41531-024-00676-4
Fasaludeen A, McTague A, Jose M, Banerjee M, Sundaram S, Madhusoodanan UK, Radhakrishnan A, Menon RN, Genetic variant interpretation for the neurologist - A pragmatic approach in the next-generation sequencing era in childhood epilepsy, Epilepsy Res., 2024, 201:107341, https://doi.org/10.1016/j.eplepsyres.2024.107341
Deepthy Chandran, Syam Krishnan, Madhusoodanan Urulangodi*, Srinivas Gopala*, Exosomal microRNAs in Parkinson?s disease: insights into biomarker potential and disease pathology, Neurological Sciences, 2024, , https://doi.org/10.1007/s10072-024-07439-2
Anand Binu, Easwer HV, Prakash Nair, Antony Stanley, Biren Khimji Patel, Madhusoodanan Urulangodi, Geetha Mandagini, Tania Jose , Role of Copeptin in predicting Post operative Hyponatremia and Hypernatremia in patients undergoing endoscopic pituitary adenoma surgery, Neurosurgery, 2024, March 29, 2024, https://doi.org/10.1227/neu.0000000000002927
Vasu MM, Koshy L, Ganapathi S, Jeemon P, Madhusoodanan U, Gopala S, Greeva P, Anitha A, Reethu S, Divya P, Shamla S, Sumitha K, Madhavan M, Vineeth CP, Kochumoni R, Harikrishnan S, Identification of novel endogenous control miRNAs in heart failure for normalization of qPCR data, Int J Biol Macromol, 2024, 2024 Jan 27:129714
Pravi Vidyadharan, Santhi CKV, Anjali Sethumadhavan, Srinivas Gopala, Cibin T Raghavan, Madhusoodanan Urulangodi*, Functional assessment of DNA extraction methods from frozen human blood samples for Sanger sequencing analysis, Cellular and Molecular Biology, 2023, 69(8): 25-33, http://dx.doi.org/10.14715/cmb/2023.69.8.4
Aishwarya Babu, Madhusoodanan Urulangodi*, Chemotherapy-induced neuronal DNA damage: an intriguing toolbox to elucidate DNA repair mechanisms in the brain, Genome Instability & Disease, 2023, , https://doi.org/10.1007/s42764-023-00110-8
Rudrabhatla PK, Divya KP, Alfiya F, Ramshekhar N. Menon, Ajith Cherian, Madhusoodanan Urulangodi, Soumya Sundaram, Generalised stiffness in hereditary hyperekplexia responsive to trihexyphenidyl: a novel finding., Clinical Pediatrics, 2023, Oct 29:99228231203300., https://doi.org/10.1177/00099228231203300
Asish Vijayaraghavan, Madhusoodanan Urulangodi, Karthika Ajit, Soumya Sundaram, Syam Krishnan, Movement disorders in GRIA2-related disorder - expanding the genetic spectrum of developmental dyskinetic encephalopathy., Movement Disorders Clinical Practice, 2023, 10(8):1222-1224, https://doi.org/10.1002/mdc3.13797
Soumya Krishnamoorthy, Gurpreet Singh, Sapna Erat Sreedharan, Deepa Damayanthi, Srinivas Gopala, Madhusoodanan UK, Sylaja PN, Soluble ST2 Predicts Poor Functional Outcome in Acute Ischemic Stroke Patients., Cerebrovasc Dis Extra, 2023, 13(1):33-40, https://doi.org/10.1159/000529512