PDF: The University of Tsukuba, Japan (2000-02)

PhD: University of Kerala, India (1997)

MSc: University of Calicut, Kerala, India (1986)

BSc : University of Calicut, Kerala, India (1984)

Scientist -G: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (2015 to present)

Scientist-F: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (2011-15)

Scientist-E: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (2007-11)

Scientist-D: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (2003- 07)

Scientist-C: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (1998-03)

Scientist-B: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (1994-98)

Member: The Joint FAO/WHO Expert Committee on Food Additives (JECFA). [Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO]

Adjunct Professor: Indian Institute of Technology, Hyderabad

Adjunct Professor:Jamia Hamdard University, New Delhi

Visiting Professor :Bharat Institute of Higher Education and Research, Chennai, India

Member: Expert Committee on RCGM (Review Committee on Genetic Manipulation, Department of Biotechnology, Govt. of India, New Delhi

Certificate of appreciation from Hon. Minister of Science and Technology, Govt. of India for the contribution to India getting full adherent status on GLP from OECD , New Delhi (NGCMA, DST, 2011)

Visiting Professor: Graduate School of Interdisciplinary New Science, Toyo University, Japan

Visiting Researcher: Bio Nano Electronics Research Centre, Toyo University, Japan

JSPS Bridge Fellowship, 2012, Japan Society for Promotion of Science, Govt. of Japan

Senior Toxicologist Fellowship' award by the International Union of Toxicology (IUTOX), USA (2010)

JSPS Postdoctoral fellowship award, 2000, Japan Society for the Promotion Sciences, Govt. of Japan

STOX/ASAW-Surajben Jethalal Thaker Prakruti Mandir Gold medal Award (2009)

Shared Thomas Edison Award-2014: Excellent research in Free Radicals and Antioxidants.

Shared Best Poster award at the 2nd International Summit on Toxicology, 7-9 October, 2013, Las Vegas, USA.

Country Correspondent for the World Library of Toxicology, USA, 2010

Certified Biological Safety Specialist, NAMSA, USA, 2009

National GLP Inspector, NGCMA, DST, New Delhi.

Secretary General of Society of Toxicology, India (2006-2012)

Chairman, South Chapter, Indian JSPS Alumni Association (2010-2013).

General Secretary, Indian JSPS Alumni Association (2013-present)

Secretary General, Association of Toxicology, India (2012 to 2013)

Associate Editor: Expert Reviews of Immunology, Vaccines and Informatics [Exp Rev Immunol Vaccine Informat] journal

Editorial Board member: Toxicology International Journal

Editorial Board member: International Journal of Medical Nano Research

Editorial Board member: International Journal of Composite and Constituent Materials

Editorial Board member: International Journals of Nanobiotechnology

Editorial Board member: International Journal of Bioincs and Bio-Materials

Organizing Secretary: Three Days Intensive Residential Training Programme on 'Toxicity, Safety, Biocompatibility Evaluation of Materials, Medical devices and Combination Products', Trivandrum, 17-19 February 2014

Organizing Secretary: International Conference on Futuristic Science and Technology in Frontier areas & 2nd Annual Conference of Indian JSPS Alumni Association (INDO-JAPAN), Thiruvananthapuram, Kerala, India, August 5-6, 2011

Organizing Secretary, INDO-US symposium on GLP: emphasis on medical devices, 5-7, March 2008, Trivandrum

Organizing Secretary: Silver Jubilee Year celebrations of Society of Toxicology and National Symposium on Good Laboratory Practice and regulatory issues, October 28-30, 2004 at SCTIMST, Trivandrum

Life Time Achievement Award to Dr. PV. Mohanan, scientist-G, Toxicology Division by Dr. Vasantharaj David Foundation, Chennai, for his outstanding contribution in toxicology and higher education.

Senior Toxicologist Fellowship, 2010, International Union of Toxicology, USA.

Certified Biological Safety Specialist by NAMSA, USA.

STOX/ASAW ? Surajben Jethalal Thaker Prakruti Mandir Gold medal Award (2009).

JSPS Postdoctoral fellowship award, 2000 by the Japan Society for the Promotion Sciences, Govt. of Japan.

Lifetime Achievement Award , Society of Toxicology India

Toxicity/biocompatibility studies of materials and Medical devices

Toxicology of nanomaterials and immunotoxicity

Toxicology of Pharmaceuticals, Agrochemicals and cosmetics

Toxicology of tissue engineered medical products, combinational products

Regulatory Toxicology

Development of alternative test system for animal experimentation.

Good Laboratory Practice and ISO 17025

Development of National GLP Guidelines for Medical devices

Mr. Joseph X, PhD Scholar (2022) Imperial College, London, under Common wealth-Split Fellowship: Organ-on-a-chip for the assessment of Nano-based therapeutics (International student exchange program).

Ms. Anju S, PhD Scholar (2022): University of Brighton, UK, under Newton-Bhabha Fund Placement Program: Synthesis, characterization and molecular toxicity of tungsten disulphide (WS2) quantum dots using human embryonic kidney (HEK) cell lines (International student exchange program).-not availed.

Ms. Ashtami J, PhD Scholar (2021): University of Houston, USA Fullbright Fellowship 2020 : Synthesis, characterization and biocompatibility evaluation of 2D Zn-Al layered double hydroxides (LDHs) using MC373-E1 osteoblastic cells (International student exchange program).

Ms. Athira SS, PhD Scholar (2021): Purdue University, USA, under SERB-OVD Fellowship, Govt. of India: Neuroprotective activity of micocycline loaded TiO2 nanotubes in adult zebrafish (International student exchange program).

Ms. Sruthi S, PhD Scholar (2015): University of Bourgogne, France, under Raman Charpak fellowship: Evaluation of molecular toxicity of zinc oxide nanoparticles and titanate nanotubes using astrocytes (International student exchange program).

Ms. Reshma SC, PhD Scholar (2015): University of Brighton, UK, under Commonwealth Split Program: Investigation of neurotoxicity and oxidative stress of PEGylated nanographene using rat (PC-12) neuronal cell lines (International student exchange program).

Ms. Syama S, PhD Scholar (2014): University of Lorraine, France, under Raman-Charpak fellowship: Assessment of molecular toxicity of PEGylated nanographene (International student exchange program).

Toxicity/biocompatibility studies of materials and Medical devices

Toxicology of nanomaterials, immunotoxicity

Regulatory Toxicology

Development of alternative test system for animal experimentation

Good Laboratory Practice and ISO 17025

Mohanan PV, Akhil V, Joseph X, Arathi A (2021) Multi-organ-on-a-Chip? with radial microfluidic channel for preclinical evaluation (File No. 202141039627/01.09.2021)

Mohanan PV, Arathi A, Akhil V, Joseph X (2021) Human-on-a-chip? for biological evaluation. File No. 202141022687/21.05.2021

Mohanan PV, Joseph X, Akhil V, Arathi A (2021) A construct of vascularised multi-organ-on-a-chip. File No. 202141014826/31.03.2021.

Mohanan PV, Remya NS (2019) A composite sponge for hemostatic and wound healing applications. Filed No. 202041001482, 13/01/2020

Mohanan PV, Siddharth Banerjee, Muralidharan CV, Lissy K Krishnan, Bhuvaneshwar GS. Development of an 'A Method for evaluating pyrogenicity in vitro and a kit therefor'. Indian Patent: Application No.1028/CHE/2012 A. Publication Date : 15/08/2014

Fellow, The National Academy of Science India (FNASc)

Fellow of Royal Society of Biology, UK (FRSB)

Fellow of Society of Toxicology, India [FST]

Fellow of Academy of Sciences for Animal Welfare [FASc (AW)]

Fellow of Society for Applied Biotechnology (FSAB)

Fellow of Royal Society of Biology - FRSB (UK)

Life member, Society of Toxicology (STOX), India,

Life Member, Indian JSPS Alumni Association, India

Life member, The Academy of Sciences for animal welfare, India

Life Member, Association of Toxicology, India

Life Member, Indian Society of Toxicology,

Life Member, Environmental Mutagen Society, India,

Life Member, Society for Biomaterials & Artificial Organs, India

Life Member, Materials Research Society of India

Life Member, Society for Tissue Engineering and Regenerative Medicine, India

Member in Indian Chapter of the Society of Quality Assurance (ICSQA) affiliated to International Society of Quality Assurance (SQA)

Development of Centrifugal Blood Pump with drive unit and flow meter for extracorporeal cardiopulmonary bypass.

Development of para-corporeal left ventricular assist device

Development of Aortic Stent Graft for endovascular treatment of thoracic aortic aneurysms

Development of a deep brain stimulator system for movement disorders

Bioactive Material Platform for drug delivery in bone

Development of intracranial electrodes for use in acute and chronic electrocorticography

An injectable hydrogel for repair of cartilage injury and growth plate defects

Lint free absorbent dressing for surgical and highly exudating chronic wounds

Alginate scaffold with recombinant growth factors for enhanced wound healing

Development of Nitinol based Occlusion Devices for non-surgical closure of Atrial Septal Defect

Development of Human-on-a-chip device technology: A paradigm shift in biological evaluation and disease model (311.8Lakhs)

Anti-microbial peptide (LL37) loaded multifunctional 3D collagen scaffold for vascularized bone tissue regeneration: India-Japan joint project

Development of Biomimetic Strontium Incorporated Nanostructured Ceramic Coatings on Cp-Titanium for Orthopaedic Implants. DBT Joint Project-Anna University+ SCTIMST

Molecular and immuno-toxicological effects of Dextran coated Ferrite and hydroxyapatite nanomaterials. Nanomission, DST, New Delhi

In Vitro alternative test system development for Ocular Irritation. ICMR, New Delhi

Development of National GLP Guidelines & Identification and selection of National Regulatory Guidelines for Testing and Evaluation of Medical Devices. GLP Monitoring Authority, DST, New Delhi

Evaluation of molecular toxicity of newly developed materials intended for biomedical applications. ICMR, New Delhi.

Development of an In vitro pyrogen test kit: Evaluation of pyrogenicity using human whole blood. DBT, New Delhi

Development of Non-toxic Latex Formulation for Biomedical Applications. DST, New Delhi

90 day sub-chronic toxicity by intraperitoneal implantation of Coated Copper T material in wistar rats

Mammalian erythrocyte Micronucleus test of Physiological saline extract of Coated Copper T device in albino mice

Mammalian Bone marrow chromosome aberration study of Physiological Saline extract of Coated Copper T device in albino mice.

Combined chronic toxicity and carcinogenicity studies of dextran coated ferrite nanomaterial in wistar rats

Combined chronic toxicity and carcinogenicity studies of hydroxyapitate nanomaterial in wistar rats

Mammalian Bone marrow chromosome aberration study of Physiological Saline extract of High Density Polyethylene in albino mice.

Mammalian erythrocyte Micronucleus test of Physiological saline extract of High Density Polyethylene in albino mice

90 day sub-chronic toxicity by intraperitoneal implantation of degradable Polycaprolactone (PCL) based scaffold in wistar rats.

In vivo genotoxicity tests-Mammalian erythrocyte Micronucleus test of Physiological saline extract of ECSIL in albino mice.

In vivo genotoxicity tests: Mammalian Bone marrow chromosome aberration test of Ethanol-Saline extract of ECSIL in albino mice

In vivo genotoxicity tests: Mammalian Bone marrow chromosome aberration test of physiological saline extract of ECSIL in albino mice.

In vivo genotoxicity tests-Mammalian erythrocyte Micronucleus test of Sesame oil extract of ECSIL in albino mice.

Evaluation of the hemostatic efficiency of Poly [?-(1,4)-2-amino-2-deoxy-D-glucosamine], based Haemostatic dressing in albino rabbits

Toxicity study of Stent materials

Acute, sub acute and sub chronic oral toxicity of a composite drug HIVS2004

Repeated dose 90 day Oral toxicity study of Polymeric nanoparticle - NMITLI - BST001 in rats

Biological evaluation of collagen based Biomaterials

Evaluation of the efficacy of Recombinant platelet-derived growth factor on healing of experimentally induced surgical wounds in SD rats.

Highlighting the most innovative contribution ? Innovative contribution: All the technologies developed by SCTIMST were evaluated for its toxicity and biocompatibility by me or under my guidance. Toxicological studies are an integral and indispensible part of development of medical device technology. As a toxicologist at SCTIMST with 32years of experience, I have been intimately associated with all the medical devices/technologies developed at SCTIMST. The technologies deployed with my contributions are; 1. The Chitra-TTK heart valve 2. Blood bags 3. Hydrocephalus shunt 4. Oxygenator 5. Cardiotomy reservoir 6. Dental Materials 7. Bioceramics products 8. Concentric needles 9. Ophthalmic sponge 10. Emily: Intra Uterine System (IUS) etc.,

Participated at the Training programme on Medical devices-Application of risk management to medical devices as per ISO 14971 :2007, Trivandrum,27 March 2018

Participated at the 3 days training programme on Quality system ISO17025, 2018.

2 days training programme on Internal Auditors as per ISO 13485:2016, 4-5 October 2016

GLP Inspectors Refresher Course organized by National GLP Compliance Monitoring Authority, DST New Delhi at CCMB, Hyderabad

GLP Inspector course: Indian Institute of Quality Management, Dept. of Sciences and Technology, Govt. of India, India (2003)

GLP Trainers trainee course: WHO-TDR Geneva and Department of Sciences and Technology, Govt. of India, December 2003 at New Delhi

GLP (Good Laboratory Practices) and its relevance in India, at New Delhi (March 1998)

ISO 17025 Training: Trained in International Standard ISO/IEC 17025:2005 (General requirements for the competence of testing and calibration laboratories)

Trained in the Quality policy and Internal audit for Accreditation of laboratories by National Accreditation Board for Laboratories, Dept. of Sciences and Technology, Government of India

DABT course (2007): completed a mid American toxicology course `Diplomate of American Board of Toxicology (DABT)? during 8-12, October 2007, at Advinus Therapeutics Pvt. Ltd., Bangalore.

WHO-TDR Training: (2005) completed a `non-clinical safety testing of products? organized by TDR of WHO during 24-26 October 2005 at New Delhi

In "Mammalian cytogenetics" at Genetic Toxicology and Chromosomal studies section, Bhaba Atomic Research Centre, Mumbai, INDIA (July 1992).

Member: The Joint FAO/WHO Expert Committee on Food Additives (JECFA). [Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO]

Chairperson: Expert committee for review of proposals under the ICMR-DFG call for Proposals 2022, ICMR Head Quarters, New Delhi

Co-Chair & Member: Interdisciplinary Biological Sciences of the Search-cum-selection committee for SERB-Power grant, SERB, DST New Delhi (2023-2026)

Member: Empowered committee on the 'Rapid Response Regulatory Framework for COVID-19 to deal with applications for development of vaccines, diagnostics, prophylactics and therapeutics', DBT, Govt. of India, New Delhi.

Member: Expert Committee on RCGM (Review Committee on Genetic Manipulation, Department of Biotechnology, Govt. of India, New Delhi (2019-2025)

Member: Project Advisory Committee (PAC) on `State University Research Excellence? (SERB-SURE) under SERB, DST New Delhi (2023-2026)

Member : Scientific Advisory Committee, ICMR-National Animal Resource Facility for Biomedical Research, Hyderabad (ICMR, Govt. of India).

Member : Project Evaluation Committee (PEC) to recommend CSIR-Fundamental & Innovative Research in Science of Tomorrow. CSIR-FIRST, Govt. of India (2021 to 2025)

Member: Expert Committee for review, evaluation & monitoring of proposal/projects and evaluation of SSP-TARA programme, SEED Division, DST, New Delhi

Member: Expert Committee on Scheme for Young Scientists and Technologists (SYST), Department of Science & Technology, New Delhi (2016-2021)

Member: Expert Committee on Technology Interventions for Addressing Societal Needs (TIASN), Department of Science & Technology, New Delhi (2016-2022)

Member: Scientific Panel on Food Additives, Flavorings, processing aids and materials in contact with food. Food Safety and Standards Authority of India (FSSAI), Govt of India (2020-2026)

Member: Expert group for subject of Toxicology for the Basic Medical Sciences (BMS) Division at ICMR Hqrs., New Delhi.

Member: Expert Committee for approval and review of Core Support Proposal/ projects and other projects having a budget of over One Crore, SEED Division, Department of Science & Technology, New Delhi (2016-21)

Member :Project Completion Report Evaluation Committee, Young Scientist Fast Track Scheme-Life Sciences, SERB, Govt of India ? 2021

Member : Expert Committee on National Postdoctoral Fellowship (NPDF), Science & Engineering Research Board (Govt. of India), New Delhi (2016-2021)

Member : Expert Committee on Fast Track Young Scientist (FT YS) Scheme of the SERB for the implementation of Early Career Research Award (ECRA) SERB (Govt. of India), New Delhi (2016-2021)

Member: Working Group to Review the current Biosimilar guidelines, DBT, New Delhi

Chairman: Selection board for the scrutinizing the candidates for Masters and PhDs in Biotechnology under MEXT Scholarship, Japan (2016-2021)

GLP Inspector: National GLP Compliance Monitoring Authority, DST, India (2003-2017)

Head, Dept of Applied biology (2022-2024)

Technical Manager, Biomedical Technology Wing (2018- March 2023),

Associate Dean (PhD Affairs) (2021- February 2023),

Dr. PV. Mohanan, Scientist-G & Head, Toxicology Division

Dr. Remya NS, Scientist-D

Dr. Megha KB, Post Doctoral Fellow

Dr. Sangeetha VP, Research Associate

Ms. Reeja Rani, Technical Asst (Lab)

Mr. Shaji S, Supportive Staff

Mr. Sudheesan D, Supportive Staff

Mr. Hari Kumar G, Supportive Staff

Ms. Athira SS, PhD Scholar

Ms. Ashtami J, PhD Scholar

Mr. Joseph Xavier, PhD Scholar

Ms. Reshma S, PhD Scholar

Mr. Amir Suhail U, PhD Scholar

Mr. Ajai krishnan MJ, PhD Scholar

Biomedical Applications and Toxicity of Nanomaterials. Published by M/s Springer Publication (https://doi.org/10.1007/978-981-19-7834-0)

Biomedical Product and Materials Evaluation: Standards and Ethics. Published by M/s Elsevier Ltd, UK. ISBN: 978-0-12-823966-7 (print), ISBN: 978-0-12-824173-8.

Microfluidics and Multi Organs on Chip. Published by M/s Springer Publication

Nanomaterials and Hazard Assessment: Published by Educational Book Centre, Mumbai, India. ISBN 9788190362615, 2012

Good Laboratory Practice and Regulatory Issues: Published by Educational Book Centre, Mumbai, India. ISBN 81-903626-0-7.

Good Laboratory Practice: emphasis on medical devices: Published by SCTIMST, Trivandrum, Kerala, India, 2009, ISBN 978-81-908710-0-6.

Publications: 270 (209 publications in journals + 39 book chapters + 22 online reports in Atlas of Science & Science Trends), edited 3 books and 4 conference proceedings, 165 presentations

Mr. Ajai Krishnan MJ 2022/PHD/07 CSIR, New Delhi: Multi organ on a chip for toxicity evaluation of target organs (ongoing)

Mr. Amir Suhail U 2021/PHD/12 UDC, New Delhi: Toxicology: a multi-organ-on-a-chip consisting of blood-brain-barrier for the assessment of nanotoxicology (ongoing)

Ms. Reshma S 2021/PHD/08 CSIR, New Delhi: Toxicology: Design and fabrication of organ-on-a-chip for toxicity evaluation (ongoing)

Mr. Joseph Xavier 2020/PHD/01 DST, New Delhi: Toxicology: Multi-organ chip for the disease model and the assessment of nano-based therapeutics (ongoing)

Ms. Ashtami Jayakumar 2018/PHD/02 SCTIMST, Trivandrum: Toxicology: Biological interactions of 2D Zn-Al layered double hydroxides (LDHs) in in vitro and in vivo systems (completed)

Ms. Athira SS 2017/PHD/14 CSIR, New Delhi: Toxicology: bio-nano interactions of polymer-coated Titanium dioxide nanotubes (completed)

Ms. Anju Surendranath 2018/PHD/05 UGC-CSIR, New Delhi: Toxicology: Molecular toxicity, bio-distribution and foetoplacental transmission of Tungsten disulphide (WS2) quantum dots using rat model (2021)

Ms. Prajitha N 2017/PHD/13 CSIR, New Delhi: Toxicology: Investigation of Interleukin-1? from pooled human blood stimulated with toxicants and associated molecular toxicity (2021)

Dr. Reshma VG 2015/PhD/08 Inspire DST, New Delhi: Investigation of toxicity of Zinc Selenium/Zinc Sulfide (ZnSe/ ZnS) Quantum dots at molecular level (2020)

Dr. Sruthi S 2013/PhD/11 UGC, New Delhi: Toxicology: Interaction of brain astrocytes with Zinc oxide nanoparticles (ZnO NPs) and related inflammatory, immuno and neurotoxicological response using rat model (2018)

Dr. Reshma SC 2013/PhD/09 ICMR, New Delhi: Integration of nanographene with rat neonates cerebellar granule neurons and associated toxicity: An in vitro and in vivo approach (2017)

Dr. Syama S, 2012/PHD/09 ICMR, New Delhi: Interfacing of nanographene with mouse bone marrow mesenchymal stem cells and its allied molecular toxicity using in vitro and in vivo methods (2016)

Dr. Sheeja LE, 5962/2009 CSIR, New Delhi: Immuno and molecular toxicological evaluation of dextran stabilized ferrite nanoparticles (2015)

Ms. Sukanya VS : Toxicity of Poly(?-caprolactone) using mouse bone marrow mesenchymal stem cells (2014)

Ms. Rasmita TR : Bone marrow derived mesenchymal stem cells as a model for in vitro toxicological evaluation (2013)

Ms. Sreelakshmi Nair: The influence of cryopreservation on IL-1? release by pooled human lymphoxcyte in response to lipopolysaccharide and lipoteichoic acid (2012)

Ms. Lakshmi N : Evaluation of Interleukin 1? levels from isolated human lymphocytes in response to pyrogens (2011)

Ms. Megha KB : Evaluation of hematological and cytokine release from cryopreserved blood in response to lipopolysaccharide (2010)