Dr. Shiny Velayudhan
Scientist 'F'
Phone : 04712520341 (O); 8547357351 (Mobile)

Ph.D, SCTIMST, Trivandrum, 2005

M.Tech (Polymer Technology), CUSAT, Cochin, 1999

M.Sc (Chemistry), University of Calicut, Calicut, 1996

B.Sc. (Chemisry), Providence Women?s College, Calicut, 1994

AISCE, Kendriya Vidyalaya, Calicut,1991

AISSC,E Kendriya Vidyalaya, Calicut, 1989

Scientist - E, SCTIMST, Trivandrum 26 July 2020 till date

Scientist - D, SCTIMST, Trivandrum, 26 July 2017 to 26 July 2020

Scientist - D (Adhoc), SCTIMST, Trivandrum, 01 March 2017. 24 August 2017

Principle Investigator, DBT, BioCare Scheme, SCTIMST, Trivandrum, 14 February 2014. 31 May 2017

Lecturer (Adhoc), National Institute of Technology, Calicut, August 2012. January 2014

Scientist - C (Adhoc), SCTIMST, Trivandrum, February 2009. August 2012

Post Doctoral Fellow, The University of Queensland, Brisbane, Australia, Nov 2005. Nov 2008

Visiting Scientist, Institute for Composite Materials, Germany, October 2001-December 2004

Best Oral Presentation Award (Scientist Category) at 35th Kerala Science Congress held at Mar Baselio Christian College of Engineering and Technology, Idukki during 12-14 February 2023

Biomedical Scientist 2019 awarded by Scire Science in the International conference of SciCon Series on In Sync-with Next Generation Biosciences (INGB-2019) held at Goa, India during 06-08 November 2019, for the outstanding contribution in the field of expertise.

MAHE Award for the best paper (2012), Society of Biomaterials and Artificial Organs India.
Travel Award (2004), Council of Industrial and Scientific, Govt of India.
Travel Award (2004), Department of Science and Technology, Govt of India.
Travel Award (2003) European Society of Biomaterials, Germany.
Best seminar award (2001), in connection with the Golden jubilee celebrations IIT Kharagpur
Bajpai-Saha award (2000) for the best paper presented at the International conference organized by the Society of Biomaterials & Artificial Organs of India, IIT Kharagpur

Processing and evaluation of polymer and polymer composites for biomedical applications

Polymeric micro-devices for drug delivery applications

Designing in bioinks for three-dimensional bio-printing

Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu

Central Manufacturing Technology Institute, Bangalore

Precision Extrusion Deposition of polymer-ceramic composites for cranio-facial applications

Synthesis and characterization of novel polymers for applications such as bio-printing and tissue engineering.

Development and characterization of polymeric micro-devices for drug delivery applications.

Shiny Velayudhan, Maya Nandkumar, Anil Kumar PR, Manoj Komath and Anugya Bhatt. Oropharyngeal swab. Application No: 202041015783, Date of filing 11/04/2020; Status: RQ filed

Roopesh R. Pai, Anilkumar PR and Shiny Velayudhan. 3D Spheroid Culture Chamber. Design registration number: 330249-001. : Design Accepted and Published on 19/06/2020.

Shiny Velayudhan, Anil Kumar PR, Kumary TV and Kalliyana Krishnan V. A polymeric hydrogel system for three-dimensional (3D) printing. Reference number: 201741021062.

Babitha Sumathy, Shiny Velayudhan and Prabha D. Nair. A bi-layered polymeric scaffold with arrayed micro-pits for full-thickness skin construct. Indian Patent Granted on 17/10/2021 Patent Number: 377860

Anil Kumar PR, Shiny Velayudhan, Roopesh R. Pai, Kumary TV and Kalliyana Krishnan V. Bioreactor for culture of mammalian cells. Application No: 285926. Design Accepted and Published, 07/12/2018

Shiny Velayudhan and Prabha D. Nair. Polymeric micro-needles for controlled delivery of drugs/biomolecules and a process for the preparation thereof. Application No: 5408/CHE/2015; Date of filing 09/10/2015; Status: FER issued on 30/12/2020; Reply to FER submitted on 25/06/2021

Research fellowship under the Bio-Care Scheme from Department of Biotechnology, Govt of India, 2014-2017.

Australian Postdoctoral Fellowship, The University of Queensland, Brisbane, Australia, 2005-2008. The University of Queensland, Australia.

DAAD fellowship: 3 years personnel exchange program funded co-jointly by DST (India) and DAAD (Germany).

Gate fellowship: Qualified the Graduate Aptitude Examination, GATE-''97. Percentile score: 91.

Life member in Additive Manufacturing Society of India.

Life member in Society of Polymer Science of India
Life member In Materials Research Society of India
Life member in Society of Biomaterials and Artificial Organs, India.
Member in Australian Society of Biomaterials (2005-2009)

Co-Principal Investigator in Efficacy Evaluation of 3D Bioprinted Liver Constructs Established from Niche Specific Bioink and Stem Cell Derived Hepatocyte Like Cells. Core Research Grant ??? Science and Engineering Research Board, GoI

Co-Principal Investigator in Pre-validation of in vitro hepatotoxicity test of drugs . Funding agency SCTIMST (TDF Program)

Phase Principal Investigator in the project entitled `3D printing of liver tissue constructs for in vitro hepatotoxicity testing. Funding agency SCTIMST (TRC program); (2016-2019); Rs. 3,40,59,000.

Principal Investigator in Development of cell encapsulated click gels as bioinks for 3D bioprinting. Funding agency SCTIMST (TDF Program); (2017-2019); Rs. Rs. 8,11,000.

Principal Investigator in Controlled Delivery of Biological Molecules using Biodegradable Microneedles. Funding agency: Department of Biotechnology, GoI; (2014-2017); Rs. 43, 80, 000.

Principal Investigator (BioCare Program) at Division of Tissue Engineering and Regeneration Technologies, Department of Applied Biology, BMT Wing, SCTIMST, India. (2014 - 2017)

Lecturer in Chemistry at National Institute of Technology, Calicut, Kerala, India. (2012-2014).

Scientist - D (Adhoc) at Division of Tissue Engineering and Regeneration Technologies, Department of Applied Biology, BMT Wing, SCTIMST, India. (2009 - 2012)

Post Doctoral Research Fellow at Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Australia, 2005-2008.

Multi-Organ Simulation Flow System Intended for Toxicity Testing. (MTech, Biotechnology, Vellore Institute of Technology, Vellore), 2021-22.

Assessing Printability Of Carboxymethyl Cellulose-Gelatin Bioinks: Optimization Of Hydrogel Compositions And Printing Parameters (BTech, Biotechnology, Vellore Institute of Technology, Vellore), 2019-2020

Gelatin Methacylamide Hydrogels for 3D Bio-printing of Skin (MPhil, Biomedical Technology), SCTIMST, 2019-2020.

Delivered a lecture on Injectable hydrogels for Bioprinting in the (5 day Seminar Series on Advanced Biomaterials for Biomedical Applications organized by BMS College of Engineering and BMT Wing of SCTIMST.

iDelivered an Invited Lecture on "Controlled Delivery of Biomolecules using Polymer Microneedles" in International Online Conference on Materials Science and Technology (ICMT 2021) 12-14 November 2021 organized by Mahatma Gandhi University, Kottayam, Kerala, India.

Keynote lecture: Delivered a Keynote Lecture on Development of Indigenous Polymeric Devices for Healthcare Applications in connection with DST-KSCSTE- Webinar Series- Theme - Women In STEM.

Delivered an invited talk on "Bio-inks: Characterization & Evaluation" at the Current Trends and Challenges in 3D Bioprinting Technology-2020 (CTC3DBT -2020) 5th July 2020 (Zoom webinar), Organized by VIT, Vellore.

Delivered a talk on "Bionks characterization and evaluation" at the webnair series jointly organized by Centre for Biomaterials, Cellular and Molecular Thernostics (CBCMT) and Vellore Institute of Technology (VIT), 5 July 2020.

Delivered a talk on "Biomaterials in Tissue Engineering" at Two days workshop on Materials in Medicine, organized by IIPC, SCTIMST on 6-7 February 2020.

Delivered a talk on "An introduction to materials, properties and the need for characterization" at Two days workshop on An Insight into Analytical Instruments For Research ??? Special Call For SC/ST Candidates, organized by IIPC, SCTIMST on 23-24 January 2020.

Delivered a talk on "Scaffolds in Tissue Engineering" at Two days workshop on Tissue Engineering for Medical Applications", organized by IIPC, SCTIMST on 5 - 6 December 2019.

Delivered a talk on "Biomaterials for Tissue Engineering" at Two days workshop on Tissue Engineering for Medical Applications, organized by IIPC, SCTIMST on 5 - 6 December 2019.

Delivered a talk on "Biomaterials for Tissue Engineering" at Two days workshop on Tissue Engineering for Medical Applications, organized by IIPC, SCTIMST on 20-21 November 2019.

Delivered a talk on "Advances in Biomedical Research" at NETHRA (New Era of Teaching and Higher Learning Through Research Activities) as Resource Person (teacher Mentor) in two days Residential Science Camp for students in connection with Rashtriya Avishkar Abhiyan, organized by Department of Chemistry, National Institute of Technology, Calicut, Kerala on 12-13 July 2019.

Delivered a talk on "Polymers in Health Care??? at CHRYSALIS" 2 Day residential workshop as Resource Person (teacher Mentor) in connection with Rashtriya Avishkar Abhiyan, organized by jointly by District Panchayath Kozhikode and Department of Chemistry, National Institute of Technology, Calicut, Kerala on 22, 23 December 2018.

Delivered a talk on "Functionalized Hydrogels for 3D Bioprinting" as Resource Person in connection with Faculty Development Programme, sponsored by Ministry of Human Resource Development, Government of India" TEQIP III on Functional Materials and Devices organized by Department of Chemistry, National Institute of Technology, Calicut, Kerala, Under Twinning with GEC Bharatpur, 10- 15 September 2018.

Delivered a talk on "Novel polymeric microneedle devices for therapeutic applications and smart bio-inks" at Wake Forest Institute for Regenerative Medicine, Wake Forest, USA, 21 May, 2018.

Delivered a lecture on "3D Bioprinting: Printing your own organs" the National Conference organized by SciCon Series on Current Trends in Biosciences (CT Bio), Dunes Hotel, Cochin, 23 August 2017, Cochin, Kerala, India.

Peer Reviewed Publications: 20; Book Chapters: 8; Book Authored: 1; Patents Granted: 1; Design Registration Granted: 2; Patent applications: 4

Authored the Book: Biological Evaluation of Ethylene Vinyl Acetate "Hydroxyapatite polymer composites for cranioplasty". Shiny Velayudhan, Girish Menon and Ramesh P. Publishers Lambert Academy Publishers, Germany, 2020.

Gelatin Methacylamide Hydrogels for 3D Bio-printing of Skin (MPhil, Biomedical Technology), SCTIMST, 2019-2020.

Multi-Organ Simulation Flow System Intended for Toxicity Testing. (MTech, Biotechnology, Vellore Institute of Technology, Vellore), 2021-22.

Roopesh R. Pai, Shilpa Ajit, Anupama Sekar J, Sarath S. Nair, Anil Kumar PR and Shiny Velayudhan*. Three Dimensional Bioprinted Parenchymal Liver Construct using Radical Scavenging Gelatin Methacrylamide based bioink formulation, Bioprinting, 27 e00214, 2022.

Roopesh RP, Muthusamy S, Velayudhan S, Sabareeswaran A, Anil Kumar PR. High-throughput production of liver parenchymal microtissues and enrichment of organ-specific functions in gelatin methacrylamide microenvironment. Biotechnol Bioeng. 2022 Mar;119(3):1018-1032. doi: 10.1002/bit.28010. Epub 2022 Jan 7. PMID: 34931302.

Shiny Velayudhan (2021). Dissolvable Microneedles for Effective Immunization during Pandemic Outbreaks. J Biotech Biores. 3(2). JBB. 000558. 2021.

Shiny Velayudhan, Shilpa Ajith, Roopesh R. Pai, Ramesh Babu, Sabareeswaran A and Anil Kumar PR. (2021). A Gel Casting Tool for Fabrication of Three Dimensional Sandwich In Vitro Culture System for Cytocompatibility Evaluation of Hydrogels was published in International Journal of Pharmaceutical Sciences and Research. Velayudhan et al., IJPSR, 2021; Vol. 12(9): 4799-4706.

Velayudhan S and Nair PD. Fabrication of Honeycomb Patterned Polyurethane Membranes for Biomedical Applications, J Nanosci Nanotechnol App, 2020, 4, 101-109 (ISSN: 2577-7920).

A book chapter "Liver on a Chip" authored by Evelyn George, Shiny Velayudhan and Anil Kumar PR for the Book - Microfluidics and Multi Organs on Chip by M/s Springer Nature. (Under Production).

Lakshmi V Nair, Vineeth M. Vijayan, Anil Kumar PR, Shiny Velayudhan* and Vinoy Thomas. Additive Manufacturing of Smart Bio-nanomaterials for Chapter 16 Fabrication of Medical Implants, Wiley Publishers, USA (Under Production).

Gayathry S, Manoj Komath and Shiny Velayudhan* (2021). "Biomaterials for Medical Products" Chapter 2 in Biomedical Product and Materials Evaluation: Standards and Ethics, Elsevier Publishers, USA.

Roopesh R. Pai, Anupama Sekar J, Shilpa Ajit, Shiny Velayudhan, Naresh Kasoju and Anil Kumar PR (2021). Three Dimensional Bioprinting of Tissues and Organs Chapter 2 in Biomedical Product and Materials Evaluation: Standards and Ethics, Elsevier Publishers, USA.

Anupama Sekar J, Athira RK, Lakshmi TS, Shiny Velayudhan, Anugya Bhatt, Anil Kumar PR and Naresh Kasoju (2021). 3D Bioprinting in Tissue Engineering and Regenerative Medicine: Current Landscape and Future Prospects. In: Bhaskar B., Sreenivasa Rao P., Kasoju N., Nagarjuna V., Baadhe R.R. (eds) Biomaterials in Tissue Engineering and Regenerative Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-16-0002-9_17.

Muthusamy S, Velayudhan S, and Anil Kumar PR (2021). Hydrogel Systems for Tissue Engineering, Chapter 10 In: Drug Delivery, Nanomedicine and Tissue Engineering: Guide to Strengthen Healthcare System, Ed: Rajakumari R, Hanna J. Maria, Nandakumar Kalarikkal and Sabu Thomas, Apple Academic Press, Taylor and Francis Group, Florida, USA .

Bernadeth K Madathil Anil Kumar PR, Thomas V and Shiny Velayudhan* (2021). Nanomaterial-Based Bio Scaffolds for Enhanced Biomedical Applications. In: Pal K. (eds) Bio-manufactured Nanomaterials. Springer, Cham. https://doi.org/10.1007/978-3-030-67223-2_7

Technology Transfer: Oropharyngeal Sample Collection Kit: Testing of Covid 19 involves collection of viral load in Viral Transport Medium (VTM) using a synthetic nasopharyngeal or oropharyngeal swabs. The project proposed under TRC P8237 involved development of Phosphate Buffered Saline (PBS) and Glycerol based VTM media along with the synthetic oropharyngeal swab for collecting the samples. This swab device can be used independently or as an accessory component for the sample collection kit for specimen collection from oropharyngeal region. The technology was transferred to (i) M/s. Origin Diagnostics and Research, Kerala and (ii) M/s. Levram Life sciences Pvt. Ltd., Mumbai.0 Trademark registration: The swab was registered under the Trademark Chitra EnMesh

Article

1
Velayudhan S. Anil Kumar PR and Prabha D. Nair., A novel, single step, highly sensitive in-vitro cell-based metabolic assay using Honeycomb microporous polymer membranes., Journal of Biomedical Nanotechnology, 2015, 11, 590-599, https://www.ncbi.nlm.nih.gov/pubmed/26310066
2
Velayudhan S, Varma HK and Ramesh P., Mechanical properties of hydroxyapatite-filled ethylene vinyl acetate copolymer composites: Effect of particle size and morphology., Journal of Applied Polymer Science, 2011, 119,1594-1601., https://onlinelibrary.wiley.com/doi/abs/10.1002/app.32812
3
Jack K, Velayudhan S, Lukmann P and Justin Cooper-white., Fabrication of Nano-composite Biodegradable Polymer Scaffolds by Thermally- Induced Phase Separation, Acta Biomaterialia, 2009, 5, 2657- 2667
4
Velayudhan S, Darren Martin and Justin Cooper-white., Evaluation of dynamic creep properties of surgical mesh prosthesis using hysteresis method I a?? Uniaxial fatigue, Journal of Biomedical Materials Research Part B: Appl Biomater, 2009, 91B: 287-296, https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbm.b.31401
5
Velayudhan S, Schmitt S, Friedrich K, Varma HK and Ramesh P., Stamp forming of hydroxyapatite-polymer composites for cranioplasty: Process Optimization using a right angled V-tool, Comp Part A: Appl Manufac, 2007, 38(6), 1621-1629,
6
Velayudhan, S., Ramesh, P., Varma, H. K. and Friedrich, K., Dynamic mechanical analysis of hydroxyapatite filled ethylene vinyl acetate copolymer., Materials Chemistry and Physics, 2005, 89, 454-460, https://doi.org/10.1016/j.matchemphys.2004.10.004
7
Velayudhan S, Anilkumar TV, Kumary TV, Mohanan PV, Fernandez AC, Varma HK, Ramesh P., Biological evaluation of pliable, osteo-conductive ethylene vinyl acetate copolymer-hydroxyapatite composites intended for cranioplasty., Acta Biomaterialia, 2005, 1, 201-209, https://www.ncbi.nlm.nih.gov/pubmed/16701797
8
Sailaja GS. Velayudhan S, Sunny MC, Sreenivasan K, Varma HK and Ramesh P, Hydroxyapatite filled chitosan a??polyacrylic acid polyelectrolyte complex., Journal of Materials Science, 2003, 38, 3653-3662, https://link.springer.com/article/10.1023/A:1025689701309