Prof. K. Jayakumar
Director
Phone :
0471-2524501

M.Ch. (Cardio-Thoracic Surgery); Medical College, Trivandrum; 1987

MS (General Surgery) ; Medical College, Trivandrum ; 1984

MBBS ; Medical College, Trivandrum ; 1978

Senior Professor , Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum. ; January 2011 - continuing

Senior Professor & Head., Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum. ; January 2011 - December 2018

Professor & Head, Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum.; October 2005 - December 2010

Professor, Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum.; March 2001 to September 2005.

Professor, Department of Cardio-Thoracic Surgery, Medical College, Calicut.; October 2000 to March 2001

Associate Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum ; 1999 to 2000

Senior Registrar; Department of Cardio-Thoracic Surgery Royal Adelaide Hospital, Adelaide, South Australia ; 1996 to 1999

Associate Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum ; 1992 to 1994

Registrar; Department of Cardio-Thoracic Surgery Royal Adelaide Hospital, Adelaide, South Australia. ;1995 to 1996

Assistant Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum; 1987 to 1992

Lecturer; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum ; 1981 to 1987

Senior House Surgeon in General Medicine; Medical College, Trivandrum ; November 1979 to October 1980

Governing Body member ,SCTIMST -2006-2007

Founder Director Board member TIMED ,SCTIMST -2014 -continuing

Past President, Indian Association of Cardiovascular and Thoracic Surgeons(IACTS)

IACTS Presidential Oration ,IACTSCON 2016

Prestigious PK Sen Oration ,IACTSCON 2014

Member of the Technology Development Committee,SCTIMST,July 2008

Scientific Committee Chairman IACTSCON 2016

Meritorious services rendered to humanity - Humanity Award - Lions International - 2006

Best Doctor Award ,IMA Kazhakootam Branch 2019

Certificate in Material management, IIMM, 2013

Adult Cardiac Surgery , Aortic Surgery, Pulmonary Thromboendarterectomy , Surgical ventricular Restoration Procedures,Heart failure surgeries

F7CARD - Multicentre,International ,randomized,double blind,placebo controlled,dose escalation trial on safety and efficacy of activated recombinant factor-VII(rFVIIa/Novo seven) in the treatment of postoperative bleeding in patients following cardiac surgery requiring cardiopulmonary bypass - Extramural funded Project

SIRS Trial - International multicentric randomised double blind placebo controlled trial on effects of steroids on high risk cardiac surgical patients. PHRI, Hamilton,Canada.Mc Master University Canada

TC 2 second generation TTk Chitra - human heart valve - Pilot human trial - Collaboration with TTk Health care

PHD Guide

Guide for Mch CVTS

Examiner for Mch CVTS and Mch Vascular Surgery

Director Board Member TIMED

Member Heart team And Heart Transplant team

Perform around 300 cardiac surgeries annually

Ministernotomy Retractor for minimally invasive cardiac surgery - Patent applied

Fellow of Indian Association of Cardio Vascular and Thoracic Surgeons

Life Member - Indian Medical Association

Life Member- Indian Association of Cardiovascular and Thoracic Surgeons

Executive Committee Member - Society for Heart Failure and Transplantation

member European Association of Cardiothoracic Surgeons

Indigenous left ventricular assist device for endstage heart failure- TRC P8123 - Rs 2.45 crores - MOU for Tech transfer and Animal trials ongoing

Homograft Heart Valve Program - more than 100 successful implants

Bio prosthetic heart valve - TRC P 8129 - Rs 1.62 crore - prototype design complete- Animal trials ongoing.

TC 2 second generation TTk Chitra - human heart valve - Pilot human trial - Rs 1.2 crore

Co-invetigator - Bio bank ( ICMR funded)

F7CARD - Multicentre,International ,randomized,double blind,placebo controlled,dose escalation trial on safety and efficacy of activated recombinant factor-VII(rFVIIa/Novo seven) in the treatment of postoperative bleeding in patients following cardiac surgery requiring cardiopulmonary bypass - Extramural funded Project

SIRS Trial - International multicentric randomised double blind placebo controlled trial on effects of steroids on high risk cardiac surgical patients. PHRI, Hamilton,Canada.Mc Master Univresity Canada

Preclinical animal trial for stem cell therapy

Preclinical animal trial for modified Chitra heart valve prosthesis

Co - Principal Investigator - Effect of leukocyte depleted blood transfusion on post operative recovery

Stem cell treatment for patients with ischemic heart disease

Co - Principal Investigator - Effect of leukocyte depleted blood transfusion on post operative recovery

Lecturer, Department of Cardiothoracic Surgery, Medical college, Trivandrum (1981 - 87)

Assistant Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum; 1987 to 1992

Registrar; Department of Cardio-Thoracic Surgery Royal Adelaide Hospital, Adelaide, South Australia. ;1995 to 1996

Associate Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum ; 1999 to 2000

Associate Professor; Department of Cardio-Thoracic Surgery at Medical College, Trivandrum ; 1992 to 1994

Senior Registrar; Department of Cardio-Thoracic Surgery Royal Adelaide Hospital, Adelaide, South Australia ; 1996 to 1999

Professor, Department of Cardio-Thoracic Surgery, Medical College, Calicut.; October 2000 to March 2001

Professor, Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum.; March 2001 to September 2005.

Professor & Head, Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum.; October 2005 - December 2010

Senior Professor & Head., Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum. ; January 2011 - December 2018

Senior Professor , Department of Cardiovascular & Thoracic Surgery; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum. ; January 2011 - continuing

HOCM outcome following Myectomy - A retrospective analysis

Progression of Tricuspid regurgitation in post operative cases of rheumatic mitral stenosis/regurgitation without addressing tricuspid regurgitation

Outcome of Surgeries in Supravalvar Aortic Stenosis

Effect of Surgical Closure of Atrial Septal defect on tricuspid regurgitation - A retrospective Analysis

Trained over 100 cardiac Surgeons

Head of department of Cardio vascular and thoracic Surgery, SCTIMST for 14 years from 2005 - 2018.

Pioneer for Coronary artery bypass Grafting in Kerala and India

Successful Aortic Root replacement program in the country

Investigator for 2 major international Trials

Principal Investigator for Multiple Device/ product development Projects (Left ventricle Assist device/ Bio-prosthetic heart valve)

Trained over 100 cardiac surgeons

Indigenous left ventricular assist device for endstage heart failure- TRC P8123 (ongoing)

Bio prosthetic heart valve - TRC P 8129 (ongoing)

TC 2 second generation TTk Chitra - human heart valve - Pilot human trial (ongoing)

F7CARD - Multicentre,International ,randomized,double blind,placebo controlled,dose escalation trial on safety and efficacy of activated recombinant factor-VII(rFVIIa/Novo seven) in the treatment of postoperative bleeding in patients following cardiac surgery requiring cardiopulmonary bypass - Completed

SIRS Trial - International multicentric randomised double blind placebo controlled trial on effects of steroids on high risk cardiac surgical patients.(Completed)

Preclinical animal trial for stem cell therapy (Completed)

Preclinical animal trial for modified Chitra heart valve prosthesis (Completed)

Co - Principal Investigator - Effect of leukocyte depleted blood transfusion on post operative recovery (Completed)

Stem cell treatment for patients with ischemic heart disease (Completed)

Co - Principal Investigator - Effect of leukocyte depleted blood transfusion on post operative recovery (Completed)

CTCME-2003,Trivandrum

Live Workshop on Mitral valve Repair-2004,Trivandrum

51st Annual Conference of IACTS,2005,Cochin

Live Workshop on Radiofrequency Ablation of Atrial Fibrillation-2005,Trivandrum

12th Annual Conference of Vascular Society of India,VSCICON-2005,Trivandrum

CME on Heart Valves & Anticoagulation,2007,Trivandrum

Member of the Governing Body,SCTIMST,Dec2006-Dec 2007

Live workshop on High Intensity Focussed Ultrasound Ablation of Atrial Fibrillation,2008,Trivandrum

CME on Bioprosthetic Valves,2008,Trivandrum

Member of the Technology Development Committee,SCTIMST,July 2008 onwards

Workshop on Total Arterial Revascularization - SCTIMST, 2010

Workshop on minimally invasive Aortic valve replacement, SCTIMST

Workshop on Endo-vascular Vein Harvesting - SCTIMST, 2010

Organising Secretary Annual Meeting of IACTS - IACTSCON 2014

Workshop on Aortic Valve repair - The Ozaki Technique, SCTIMST, 2019

Minimally invasive Mitral valve replacement , SCTIMST 2019

As Head of the department for 14 years have led a team of nationally and internationally trained cardiac surgeons to develop the department into one of the best in the country

As President of Indian Association of Cardio Thoracic Surgeons - gave new directions to the whole society of Cardiac surgeons in the Country

Member Heart team - SCTIMST

Reviewer for Multiple national and international Cardiac surgery journals

Invited talks at multiple national and international conferences.

Panellist at multiple national and international conferences.

106 publications in national and International journals, H index 17, 788 citations

Tricuspid Regurgitation in Ostium Secundum Atrial Septal Defects: Repair or Not? P Kumar, BK Radhakrishnan, R Sudevan, J Karunakaran The Heart Surgery Forum 23 (2), E239-E244

Combined effect of left stellate ganglion blockade and topical administration of papaverine on left internal thoracic artery blood flow in patients undergoing coronary ??? R Chandran, R Sreedhar, S Gadhinglajkar, P Dash, J Karunakaran, ... Annals of Cardiac Anaesthesia 23 (2), 170

Outcomes of Mitral Valve Replacement after Closed Mitral Valvotomy: A Retrospective Cohort Study BK Radhakrishnan, R Sreekantan, VT Panicker, J Karunakaran The heart surgery forum 22 (3), E207-E212

Pulmonary Atresia with Ventricular Septal Defect: Rare Presentation with Coronary-to-Pulmonary Artery Collaterals from Both Right and Left Coronaries P Ballal, S Menon, S Babu, BS Dharan, M Kiran, SD Baruah, ... World Journal for Pediatric and Congenital Heart Surgery, 2150135118825158

Patient prosthesis mismatch and its impact on left ventricular regression following aortic valve replacement in aortic stenosis patients A Iqbal, VT Panicker, J Karunakaran Indian Journal of Thoracic and Cardiovascular Surgery 35 (1), 6-14

Endocardectomy of a coconut shell left atrium BK Radhakrishnan, P Ballal, J Karunakaran Asian Cardiovascular and Thoracic Annals 26 (9), 713-714

Acute dysfunction of tilting disc valve after mitral valve replacement A Iqbal, VV Pillai, KP Unnikrishnan, J Karunakaran IHJ Cardiovascular Case Reports (CVCR) 2 (3), 218-220

Incidentally detected mass in the right atrial-right ventricular groove S Veerbhadran, VV Pillai, J Karunakaran Asian Cardiovascular and Thoracic Annals 26 (6), 494-494

Submitral Aneurysm After Pulmonary Artery Banding???A Case Report A Iqbal, S Menon, BS Dharan, KT Raman, J Karunakaran World Journal for Pediatric and Congenital Heart Surgery 9 (3), 364-367

Intraoperative assessment of transient and persistent regional left ventricular wall motion abnormalities in patients undergoing coronary revascularization surgery using real ??? N Aggarwal, KP Unnikrishnan, I Biswas, J Karunakaran, PR Suneel Echocardiography 34 (11), 1649-1659

Double-valve intervention with staged hybrid repair for post-traumatic aortic incompetence and aortic rupture VV Pillai, AC Jeyakumar, JE Rajan, U Madathipat, J Karunakaran Indian Journal of Thoracic and Cardiovascular Surgery 33 (3), 278-279

Repair of Double Orifice Left AV Valve (DOLAVV) with Endocardial Cushion Defect in Adult VV Pillai, J Karunakaran Brazilian Journal of Cardiovascular Surgery 32 (4), 338-340

Sub-physiological oxygen levels optimal for growth and survival of human atrial cardiac stem cells DS RajendranNair, J Karunakaran, RR Nair Molecular and Cellular Biochemistry 432 (1-2), 109-122

Entrapment of guidewire in left anterior descending artery: Surgical management AM Idhrees, BK Radhakrishnan, VT Panicker, V Pillai, J Karunakaran Asian Cardiovascular and Thoracic Annals 25 (6), 457-458

Observe, excel and evolve J Karunakaran Indian Journal of Thoracic and Cardiovascular Surgery 33 (2), 104-109

Modified closed chamber sutureless technique for anomalous pulmonary venous connection S Menon, T Mathew, J Karunakaran, BS Dharan Annals of pediatric cardiology 10 (1), 58

Anomalous origin of the left coronary artery from the pulmonary artery in an infant and adult: intraoperative echocardiographic comparison K Chigurupati, S Gadhinglajkar, R Sreedhar, J Karunakaran, BS Dharan Journal of cardiothoracic and vascular anesthesia 30 (5), 1353-1357

A large left ventricular pseudoaneurysm BK Radhakrishnan, CJ Kumar, S Philipose, J Karunakaran European Journal of Cardio-thoracic Surgery 49 (4), 1291-1292

Acute Rheumatic Valvulitis with Palisading: A Rare but Classic Histopathological Finding in a Surgical Specimen AR Nair, S Samavedam, JM Tharakan, J Karunakaran Heart India 3 (4), 121

Acute Rheumatic Valvulitis with Palisading: A Rare but Classic Histopathological Finding in a Surgical Specimen AR Nair, S Samavedam, JM Tharakan, J Karunakaran Heart India 3 (4), 121

Surgery for Congenital Tricuspid Valve Cleft: Tricuspid Valve Repair with Neochordae and Annuloplasty. SP Veerbhadran, VV Pillai, B Sasidharan, J Karunakaran The Journal of heart valve disease 24 (4), 525-527

A case of rheumatic mitral stenosis with subaortic ventricular septal defect and anomalous right coronary artery from left sinus MI Abdulsamath, V Pillai, B Radhakrishnan, V Paniker, P Varma, ... Indian Journal of Thoracic and Cardiovascular Surgery 31 (2), 184-186

Intraoperative identification of chyle leak during coarctation repair using fluorescein dye T Mathew, M Idhrees, S Misra, S Menon, BS Dharan, J Karunakaran The Annals of Thoracic Surgery 99 (5), 1827

Calcific aorta and coronary artery: two cases of calcific ascending aorta and descending aorta AM Idhrees, BK Radhakrishnan, VT Panicker, V Pillai, J Karunakaran Journal of Geriatric Cardiology: JGC 12 (1), 88

A Valve in Valve: Mitral Valve Replacement with Tricuspid Annuloplasty in a Case of Mitral Annular Calcification AM Idhrees, VT Panicker, BK Radhakrishnan, V Pillai, J Karunakaran Cardiovasc Pharm Open Access 4, 166

Mohammed Idhrees Abdulsamath, Vivek Pillai, Bineesh Radhakrishnan, Varghese Paniker, Praveen Varma & J Karunakaran Indian J Thorac Cardiovasc Surg 31, 184-186

Demographic profile, clinical characteristics and outcomes of patients undergoing coronary artery bypass grafting retrospective analysis of 4,024 patients PK Varma, S Kundan, C Ananthanarayanan, VT Panicker, VV Pillai, ... Indian Journal of Thoracic and Cardiovascular Surgery 30 (4), 272-277

Primary Modified Bentall's Procedure in a Case of Laubry-Pezzi Syndrome BK Radhakrishnan, M Idhrees, S Devarajan, VT Panicker, VV Pillai, ... The Annals of thoracic surgery 98 (4), 1445-1447

Sternotomy After Classic Blalock-Taussig Shunt: A Unique Challenge A Chandrasekaran, T Mathew, S Menon, BS Dharan, J Karunakaran, ... The Annals of thoracic surgery 98 (3), 1114

Early and 1-year outcome and predictors of adverse outcome following monocusp pulmonary valve reconstruction for patients with tetralogy of Fallot: a prospective observational D Sasikumar, B Sasidharan, JA Tharakan, BS Dharan, T Mathew, ... Annals of pediatric cardiology 7 (1), 5

Repair of simple congenital cardiac defects via lower ministernotomy, using standard instruments T Mathew, M Mathew, S Menon, BS Dharan, J Karunakaran Indian Journal of Thoracic and Cardiovascular Surgery 28 (3), 155-159

Persistent left fifth aortic arch with pentalogy of Fallot AD Furtado, SRK Manohar, SK Pradhan, V Pillai, J Karunakaran The Thoracic and cardiovascular surgeon 60 (03), 233-235

Tricuspid endocarditis with indirect Gerbode: septal translocation of posterior leaflet V Pillai, S Menon, B Kottayil, J Karunakaran Heart, Lung and Circulation 20 (6), 362-364

The regurgitant mitral valve: A case of mistaken identity AD Furtado, V Pillai, V Panicker, J Karunakaran Indian Journal of Thoracic and Cardiovascular Surgery 26 (4), 277

Tricuspid valve excision using off-pump inflow occlusion technique: Role of intra-operative trans-esophageal echocardiography S Gadhinglajkar, R Sreedhar, J Karunakaran, M Misra, G Somasundaram, ... Annals of cardiac anaesthesia 13 (2), 148

The aortic rim recount: embolization of interatrial septal occluder into the main pulmonary artery bifurcation after atrial septal defect closure M Misra, A Sadiq, N Namboodiri, J Karunakaran Interactive cardiovascular and thoracic surgery 6 (3), 384-386

Long-term functional assessment after correction of tetralogy of Fallot in adulthood A Sadiq, KG Shyamkrishnan, S Theodore, S Gopalakrishnan, ... The Annals of thoracic surgery 83 (5), 1790-1795

Outcomes of surgical management of ruptured abdominal aortic aneurysm RR Bhuyan, A Sadiq, S Theodore, KS Neelakandhan, M Unnikrishnan, ... Indian Journal of Thoracic and Cardiovascular Surgery 22 (2), 132-136

Is there any change in free flow of pedicled left internal thoracic artery conduit at varying degrees of clockwise twist up to 360 AK Sarma, SKKVS Siva, J Karunakaran, NK Sankaran The Journal of thoracic and cardiovascular surgery 129 (5), 1192-1193

Revascularization for left main ostial stenosis with right internal thoracic artery in Takayasu's disease AS Sarma, S Theodore, J Karunakaran, HS Pillai, KS Neelakandhan Indian Journal of Thoracic and Cardiovascular Surgery 20 (3), 137-139

Twisting of pedicled left internal thoracic artery graft three hundred sixty degrees clockwise: Does it change the outcome AK Sarma, SAIKKVS SIVA, J Karunakaran, NK SANKARAN Journal of thoracic and cardiovascular surgery 128 (4), 617-618 2 2004 Articles 1???40

Reviewer National and International Journals

M.O.U signed for Left ventricular Assist device

New Generation Chitra Valve (TC 2 second generation TTk Chitra)

Article

1
Duara, Rajnish; Misra, Manoranjan; Bhuyan, Ritwick Raj; Sarma, P Sankara; Jayakumar, Karunakaran, Does transfusion of residual cardiopulmonary bypass circuit blood increase postoperative bleeding? A prospective randomized study in patients undergoing on pump cardiopulmonary bypass., Asian J Transfus Sci, 2008, 2; 51-5, http://www.ncbi.nlm.nih.gov/pubmed/20041077
2
Aghila Rani, Koippallil G; Jayakumar, Karunakaran; Srinivas, Gopal; Nair, Renuka R; Kartha, Chandrasekharan C, Isolation of ckit-positive cardiosphere-forming cells from human atrial biopsy., Asian Cardiovasc Thorac Ann, 2008, 16; 50-6, http://www.ncbi.nlm.nih.gov/pubmed/18245707
3
Misra, Manoranjan; Sadiq, Adil; Namboodiri, Narayanan; Karunakaran, Jayakumar, The 'aortic rim' recount: embolization of interatrial septal occluder into the main pulmonary artery bifurcation after atrial septal defect closure., Interact Cardiovasc Thorac Surg, 2007, 6; 384-6, http://www.ncbi.nlm.nih.gov/pubmed/17669873
4
Bhuyan, Ritwick R; Rajendran, Sunil; Unnikrishnan, Madhathipat; Jayakumar, Karunakaran, Successful repair of aortobronchial fistula using circulatory arrest., ANZ J Surg, 2007, 77; 398-9, http://www.ncbi.nlm.nih.gov/pubmed/17497991
5
Sadiq, Adil; Shyamkrishnan, Kumaralingam Gopalakrishnan; Theodore, Sanjay; Gopalakrishnan, Sreeram; Tharakan, Jagan Mohan; Karunakaran, Jayakumar, Long-term functional assessment after correction of tetralogy of Fallot in adulthood., Ann Thorac Surg, 2007, 83; 1790-5, http://www.ncbi.nlm.nih.gov/pubmed/17462400
6
Bhuyan, R.R.; Sadiq, A.; Theodore, S.; Neelakandhan, K.S.; Unnikrishnan, M.; Karunakaran, J., Outcomes of surgical management of ruptured abdominal aortic aneurysm, Indian Journal of Thoracic and Cardiovascular Surgery, 2006, 22; 132-136, http://www.springerlink.com/content/0027j34r05617301/
7
Sinha, Prabhat Kumar; Neema, Praveen Kumar; Unnikrishnan, Koniparambil Pappu; Varma, Praveen Kerala; Jaykumar, Karunakaran; Rathod, Ramesh Chandra, Effect of lung ventilation with 50% oxygen in air or nitrous oxide versus 100% oxygen on oxygenation index after cardiopulmonary bypass., J Cardiothorac Vasc Anesth, 2006, 20; 136-42, http://www.ncbi.nlm.nih.gov/pubmed/16616650
8
Sarma, Apurba Kumar; Krishna, Murali; Karunakaran, Jayakumar; Neema, Praveen Kumar; Neelakandhan, Kurur Sankaran, Severe hypothyroidism after coronary artery bypass grafting., Ann Thorac Surg, 2005, 80; 714-6, http://www.ncbi.nlm.nih.gov/pubmed/16039238
9
Sarma, Apurba Kumar; Siva, Sai Kiran Krishnamurthy Venkata Sathya; Karunakaran, Jayakumar; Sankaran, Neelakandhan Kurur, Is there any change in free flow of pedicled left internal thoracic artery conduit at varying degrees of clockwise twist up to 360 degrees ?, J Thorac Cardiovasc Surg, 2005, 129; 1192-3, http://www.ncbi.nlm.nih.gov/pubmed/15867809
10
Sarma, Apurba Kumar; Krishnamurthy, Sai Kiran; Siva, Venkata Sathya; Karunakaran, Jayakumar; Sankaran, Neelakandhan Kurur, Twisting of pedicled left internal thoracic artery graft three hundred sixty degrees clockwise: does it change the outcome?, J Thorac Cardiovasc Surg, 2004, 128; 617-8, http://www.ncbi.nlm.nih.gov/pubmed/15457165