श्री चित्रा तिरुनाल आयुर्विज्ञान और प्रौद्योगिकी संस्थान, त्रिवेंद्रम
Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum
The basic activities of the division are to understand the blood/tissue material interactions at the interface and develop modified surfaces for various biomedical applications such as Haemoperfusion column, Bioprosthetic Heart Valve, angiogenic and wound healing materials etc. Laboratory is also interested in modifying interfaces towards drug release studies including development of gene delivery systems, oral insulin/heparin delivery systems, artificial skin-transdermal delivery systems and possible peptide delivery system based on polymeric and inorganic nano/microparticles. Department of Science & Technology has funded to develop Facilities for nano/micro particles based biomaterials for Advanced Drug Delivery Systems (FADDS).
Infrastructure, equipments etc
Offered to Public, within institute
Indo-Spain project entitled "Development of nanodevices for DNA delivery and cell transfection using Elastin Like Polymers (ELPs) coupled to cell interaction motifs" - DST, New Delhi
Facility for micro/nanoparticles based biomaterials for Advanced Drug Delivery Systems (FADDS) - with DST, New Delhi under DPRP programme.
Oral Insulin Delivery - with CSIR, New Delhi under NMITLI programme, in collaboration with USV Ltd. Mumbai
Microparticles based Hemostatic chitosan material - with India Sea Foods, Cochin
32 patents including in Canada, European Union, Japan and USA
The projects ongoing and completed by the group relate to the development of Small Diameter Vascular Graft, Hemoperfusion Column, Artificial Wound Dressing Materials - Transdermal Delivery system, Synthesis of Hydroxyapatite, development of nanoparticles and its uses towards drug (peptide) delivery systems and coatings to enhance tissue compatibility of implants, Hemodialysis membranes, improvement of Bioprosthetic Heart valve via surface modifications, and Oral Insulin Delivery Systems (under NMITLI, CSIR, New Delhi) using pH sensitive microspheres/nanoparticles loaded with liposome/ b-cyclodextrin derivatives/ lipids encapsulated insulin. Basic activities also relate understanding of blood/tissue - material interactions at the interface. Recently Department of Science & Technology, New Delhi , has approved the Development of "Facilities for Micro/Nanoparticles based Advanced Drug Delivery Systems (FADDS)" to his laboratory with a funding of over US$ 1 million.